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Pneumovax 23
Pneumovax 23 is a pneumococcal polysaccharide vaccine used to help prevent infections caused by Streptococcus pneumoniae bacteria, including pneumonia, meningitis, and bacteremia. The vaccine contains purified capsular polysaccharides from 23 types of pneumococcal bacteria, which together account for the majority of severe pneumococcal infections. Pneumovax 23 is recommended for adults aged 65 and older, and for certain high-risk individuals who are younger, to protect against serious pneumococcal disease.
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Frequently Asked Questions
How long does Pneumovax 23 last?
The protection from Pneumovax 23 lasts for several years, but in high-risk individuals, a booster dose may be needed after 5 years.
Can Pneumovax 23 be given with the flu vaccine?
Yes, Pneumovax 23 can be administered at the same time as the influenza vaccine, but the two vaccines should be given at different injection sites.
Who should not receive Pneumovax 23?
Individuals with a history of severe allergic reactions to any of the components of the vaccine or those who are currently suffering from a moderate or severe illness should avoid or delay vaccination.
Does Pneumovax 23 prevent all types of pneumonia?
No, Pneumovax 23 protects against pneumococcal pneumonia caused by 23 strains of Streptococcus pneumoniae, but it does not protect against viral or other bacterial forms of pneumonia.
Can I get Pneumovax 23 if I’m already sick?
If you have a mild illness (like a cold), you can still get the vaccine. However, if you are experiencing a moderate or severe illness, it is recommended to wait until you recover before receiving the vaccine.
Comprehensive Drug Guide
How Does Pneumovax 23 Work?
Pneumovax 23 works by stimulating the body’s immune system to produce antibodies against Streptococcus pneumoniae bacteria. These antibodies help the body recognize and destroy the bacteria if exposed to it in the future, thereby reducing the risk of pneumococcal infections.
Common Dosages
- One dose is typically recommended for adults aged 65 and older.
- Some high-risk individuals may require a second dose after 5 years.
Typical Dosing
- For adults 65 years and older: A single dose of 0.5 mL injected either intramuscularly or subcutaneously.
- For high-risk individuals: The dosing schedule may vary depending on the individual’s condition and healthcare provider’s recommendations, with potential for revaccination after 5 years.
Typical Dosing
FDA Approved Indications
- Prevention of pneumococcal disease in adults aged 65 and older.
- Prevention of pneumococcal disease in individuals aged 2 years and older who are at increased risk for pneumococcal infections, such as those with chronic illnesses, weakened immune systems, or those who smoke.
Who Shouldn't Take Pneumovax 23?
- Known severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine or a previous dose of pneumococcal vaccine.
- Moderate or severe illness with or without fever; vaccination may need to be delayed until recovery.
Advice From The Pharmacist
- Pneumovax 23 can be given at the same time as other vaccines, but should be administered at a different injection site.
- Report any signs of allergic reactions such as hives, difficulty breathing, or swelling immediately after vaccination.
- If you have a weakened immune system or chronic illness, consult your healthcare provider about your vaccination schedule.
- Mild side effects such as soreness at the injection site, redness, and fever are common and typically resolve within a few days.
Side Effects of Pneumovax 23
Common Side Effects
- Soreness, redness, or swelling at the injection site
- Mild fever
- Fatigue
- Muscle pain
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., anaphylaxis)
- High fever
- Difficulty breathing
Risks and Warnings of Pneumovax 23
- Allergic Reactions: Patients with a history of severe allergic reactions to vaccines should discuss the risks with their healthcare provider before receiving Pneumovax 23.
- Immunocompromised Patients: Individuals with weakened immune systems may not respond as effectively to the vaccine. These patients should consult with their healthcare provider about appropriate vaccination schedules and monitoring.
- Timing of Vaccination: For patients receiving immunosuppressive therapy, it is recommended to vaccinate prior to starting such treatments or after completing the treatment to ensure a more effective immune response.
Interactions with Pneumovax 23
Common Drug Interactions
- Live vaccines: Live vaccines should be administered at a different time if not given simultaneously to avoid possible interference with the immune response.
- Immunosuppressive drugs: Medications that weaken the immune system (e.g., steroids, chemotherapy) may reduce the effectiveness of the vaccine.
Alternatives to Pneumovax 23
- Prevnar 13: A pneumococcal conjugate vaccine that protects against 13 types of Streptococcus pneumoniae, often used in combination with Pneumovax 23 in high-risk individuals.
- Flu vaccines: While not a direct alternative, receiving an annual flu vaccine is important for overall respiratory health, especially in the elderly and immunocompromised.
