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Tydemy
Tydemy is a prescription combination oral contraceptive used to prevent pregnancy. It contains two active ingredients: drospirenone (a progestin) and ethinyl estradiol (an estrogen). Tydemy also includes levomefolate calcium, a form of folic acid (vitamin B9), which helps to maintain folate levels in women and reduce the risk of neural tube defects in a potential pregnancy if the pill is stopped. Tydemy works by preventing ovulation, thickening cervical mucus to block sperm, and altering the uterine lining to prevent implantation.
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Frequently Asked Questions
How effective is Tydemy at preventing pregnancy?
Tydemy is over 99% effective when taken perfectly, but with typical use, it is about 91% effective at preventing pregnancy.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember, then take the next pill at your regular time. If you miss two or more active pills, follow the instructions in the package insert and use backup contraception for at least 7 days.
Can I use Tydemy while breastfeeding?
Tydemy is not recommended during breastfeeding, as it may reduce milk supply. Consult your healthcare provider for safer contraceptive options if you are nursing.
Can Tydemy cause weight gain?
Weight changes, including weight gain, are possible side effects of hormonal contraceptives like Tydemy, but they vary from person to person.
Is it safe to skip the placebo pills and avoid having a period?
Yes, you can skip the placebo pills and start a new pack of active pills to avoid having a period. However, it’s important to consult your healthcare provider before doing so regularly.
Comprehensive Drug Guide
How Does Tydemy Work?
- Inhibiting ovulation: The hormones in Tydemy prevent the release of an egg from the ovary.
- Thickening cervical mucus: This makes it difficult for sperm to enter the uterus.
- Altering the uterine lining: This reduces the likelihood of implantation if fertilization occurs.
Common Dosages
- Drospirenone 3 mg
- Ethinyl estradiol 0.03 mg
- Levomefolate calcium 0.451 mg
The placebo tablets contain levomefolate calcium 0.451 mg only.
Typical Dosing
- Take one tablet daily, at the same time each day.
- Start a new pack immediately after finishing the previous one, with no break between packs.
- Follow the 28-day cycle: 24 active tablets followed by 4 placebo tablets.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women of reproductive age.
- Maintenance of folate levels in women who may become pregnant.
Who Shouldn't Take Tydemy?
- History of blood clots, such as deep vein thrombosis (DVT) or pulmonary embolism (PE).
- Cardiovascular diseases, including heart attack or stroke.
- Uncontrolled high blood pressure.
- Severe liver disease or liver tumors.
- Known or suspected breast cancer or other estrogen/progestin-sensitive cancers.
- Smokers over the age of 35, due to the increased risk of cardiovascular events.
Advice From The Pharmacist
- Take Tydemy at the same time each day to ensure maximum effectiveness.
- If you miss a pill, follow the instructions provided in the package insert. For missed active pills, you may need to use backup contraception such as condoms.
- Avoid smoking while taking Tydemy, as this increases the risk of serious cardiovascular events.
- Tydemy does not protect against sexually transmitted infections (STIs); consider using condoms to reduce the risk of STIs.
- Store the medication at room temperature, away from excessive moisture and heat.
Side Effects of Tydemy
Common Side Effects
- Nausea or vomiting
- Headache, including migraines
- Breast tenderness
- Weight changes
- Irregular bleeding or spotting between periods
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Heart attack or stroke, especially in smokers over the age of 35
- Liver problems, including liver tumors
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Tydemy
- Blood Clot Risk: Tydemy increases the risk of blood clots, especially in women who smoke, are over 35, or have certain medical conditions. Women with these risk factors should consider alternative forms of contraception.
- Cardiovascular Risk: Smoking while using combination oral contraceptives like Tydemy significantly increases the risk of cardiovascular events, such as heart attack or stroke. Tydemy should not be used by smokers over the age of 35.
- Hyperkalemia Risk: Drospirenone, one of the ingredients in Tydemy, can increase potassium levels in the blood. Women with kidney disease, liver disease, or adrenal insufficiency should be closely monitored for hyperkalemia.
Interactions with Tydemy
Common Drug Interactions
- Potassium-sparing diuretics (e.g., spironolactone): The drospirenone in Tydemy can increase potassium levels, so use with caution if you are also taking potassium-sparing medications.
- CYP3A4 inducers (e.g., rifampin, carbamazepine): These drugs can decrease the effectiveness of Tydemy by increasing the breakdown of hormones.
- Antibiotics: Some antibiotics may reduce the effectiveness of Tydemy. Always inform your healthcare provider of any medications you are taking.
Alternatives to Tydemy
- Yaz: A similar combined oral contraceptive containing drospirenone and ethinyl estradiol, but with a slightly different dosing schedule.
- Lo Loestrin Fe: A low-dose estrogen oral contraceptive containing norethindrone and ethinyl estradiol.
- NuvaRing: A vaginal ring that releases a combination of estrogen and progestin for monthly contraception.
- Progestin-only pills: For women who cannot take estrogen, these birth control pills contain only progestin and may be a safer option.
