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Trulicity
Trulicity, also known as Dulaglutide, is a widely utilized injectable medication in the glucagon-like peptide1 receptor agonists drug class. It's specifically designed for the treatment of type 2 diabetes in adults. Trulicity works by stimulating the body's insulin production in response to high blood sugar levels.
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Frequently Asked Questions
Can Trulicity cause addiction?
The potential for addiction to Trulicity is not known, but overuse or misuse can lead to health complications. It's crucial to use the medication as directed by your healthcare provider.
Does Trulicity interact with other medications or foods?
Trulicity can have interactions with certain medications, significantly influencing its effectiveness. It's essential to inform your doctor about any other medications you're currently taking, including overthecounter drugs, vitamins, and herbal products.
Is Trulicity safe for pregnant or breastfeeding women?
The impact of Trulicity on pregnancy or breastfeeding is unknown; however, using the medication in these circumstances should be done after consulting with your healthcare provider.
What should I do if I miss a dose of Trulicity?
Trulicity is generally administered weekly. If you miss a dose, take it as soon as you remember, but never double the dose to compensate for the missed one. Always adhere to the instructions provided by your healthcare provider.
Comprehensive Drug Guide
How Does Trulicity Work?
Dulaglutide is a synthetic analog of human GLP-1. It works by increasing insulin secretion, reducing glucagon secretion, and delaying gastric emptying.
What is Trulicity Used For?
Dulaglutide is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Common Dosages
Injective Solution: 0.75 mg/0.5 mL, 1.5 mg/ 0.5 mL, 3 mg/0.5 mL, 4.5 mg/0.5 mL
Typical Dosing
FDA Approved Indications
- Type 2 Diabetes: Initiate at 0.75 mg subcutaneously once a week. May increase to a maximum dose of 1.5 mg once a week after 1 month for additional blood glucose control.
Off-Label Uses
It's also been used for the off-label treatment of obesity and weight management.
- Obesity and weight management: 1.5 to 3.0 mg subcutaneously once a week.
Pediatric Dosing
Not recommended for pediatric patients under the age of 18 due to lack of studies and potential harm.
Who Shouldn't Take Trulicity?
- Have a personal or family history of medullary thyroid carcinoma.
- Have a personal or family history of Multiple Endocrine Neoplasia syndrome type 2.
- Have a known hypersensitivity to dulaglutide or any of the other product components.
- Are pregnant, planning to become pregnant, or are breastfeeding (it's not known whether dulaglutide can harm the baby).
Advice From The Pharmacist
- Stick with the schedule. Dulaglutide should be taken once a week, on the same day each week.
- Inject dulaglutide under the skin (subcutaneously) in the stomach area, thigh, or outer area of the upper arm. Do not inject into a muscle (intramuscularly) or a vein (intravenously).
- Rotate the injection site each week.
- Do not use it if the solution is cloudy, discolored, or if it contains particles.
- Misuse can lead to an overdose. Don't inject more often than once a week.
- If you're feeling nauseated, let your doctor know. Dulaglutide can sometimes cause stomach issues.
- Finally, don't forget to take care of yourself! Keep all your doctor's appointments and get regular check-ups.
Side Effects of Trulicity
Common Side Effects
- Nausea
- Vomiting
- Diarrhea.
- Abdominal pain or decreased appetite.
Uncommon/Severe Side Effects
Contact your doctor urgently if you have symptoms like persistent severe stomach pain, with or without vomiting.
Risks and Warnings of Trulicity
- Patients with dulaglutide should be monitored for pancreatitis. Discontinue promptly if pancreatitis is suspected.
- There's a risk of thyroid tumors. It's not recommended for people with a family or personal history of medullary thyroid cancer and Multiple Endocrine Neoplasia syndrome type 2.
Interactions with Trulicity
Common Drug Interactions
- Insulin
- Sulfonylureas (like glimepiride)
- Thiazolidinediones (like pioglitazone)
- Dipeptidyl peptidase-4 (DPP-4) inhibitors (like sitagliptin)
Alternatives to Trulicity
- Liraglutide
- Exenatide
- Semaglutide
- Lixisenatide
- Albiglutide
