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Triderm

Triderm (triamcinolone acetonide) is a medium-potency corticosteroid used to treat various inflammatory skin conditions, including eczema, psoriasis, allergic reactions, and dermatitis. It helps to reduce inflammation, itching, and redness by suppressing the immune response in the skin. Triderm is commonly used to manage moderate to severe skin conditions.



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Frequently Asked Questions

How long does it take for Triderm to work?
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You may start noticing improvement in your symptoms, such as reduced redness and itching, within a few days of using Triderm. Full effects may take 1 to 2 weeks depending on the severity of the condition.

Can I use Triderm on my face?
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Use Triderm on the face only if specifically directed by your healthcare provider, as prolonged use in sensitive areas like the face can lead to skin thinning and other side effects.

What should I do if I miss a dose?
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If you miss a dose, apply it as soon as you remember. If it’s close to the time of your next dose, skip the missed dose and resume your regular schedule. Do not apply extra cream to make up for a missed dose.

Can Triderm cause weight gain?
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Although rare, long-term or extensive use of Triderm can lead to systemic absorption, which may cause side effects such as weight gain, especially if applied over large areas or used with occlusive dressings.

Is Triderm safe for children?
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Yes, Triderm may be prescribed for children, but it should be used with caution and under close supervision by a healthcare provider, as children are more susceptible to systemic absorption and side effects like growth suppression.

Comprehensive Drug Guide

How Does Triderm Work?

Triamcinolone acetonide works by activating glucocorticoid receptors in the skin, reducing the release of substances like prostaglandins and cytokines that cause inflammation. This leads to reduced redness, swelling, itching, and other symptoms of inflammatory skin conditions.



Common Dosages

  • 0.1% cream and 0.1% ointment for topical use.

Typical Dosing

  • Apply a thin layer of Triderm to the affected area of skin 2 to 3 times daily, depending on the severity of the condition and as directed by your healthcare provider.
  • Avoid applying to large areas of the body or sensitive areas like the face, unless instructed by your doctor.


Typical Dosing

FDA Approved Indications

  • The treatment of eczema (atopic dermatitis)
  • Contact dermatitis and other allergic skin reactions
  • Psoriasis
  • Seborrheic dermatitis
  • Other inflammatory skin conditions


Who Shouldn't Take Triderm?

  • Known hypersensitivity to triamcinolone or other corticosteroids.
  • Untreated skin infections (bacterial, viral, or fungal).
  • Rosacea or perioral dermatitis, unless directed by a healthcare provider.


Advice From The Pharmacist

  • Use Triderm exactly as prescribed, applying a thin layer to the affected areas.
  • Wash your hands before and after applying the cream, unless treating your hands.
  • Do not use Triderm on open wounds or broken skin, and avoid using it in the eyes or mouth.
  • Avoid occlusive dressings (e.g., bandages or wraps) unless instructed by your healthcare provider, as this can increase absorption and the risk of side effects.
  • Do not use Triderm for longer than recommended, especially on sensitive skin areas, to avoid side effects such as skin thinning.


Side Effects of Triderm

Common Side Effects

  • Skin irritation or dryness
  • Redness or burning at the application site
  • Itching


Uncommon/Severe Side Effects

  • Skin thinning (atrophy), especially with prolonged use
  • Stretch marks (striae)
  • Increased risk of skin infections at the application site
  • Systemic absorption, potentially leading to side effects such as weight gain, high blood sugar, or suppression of adrenal gland function (with long-term use or large applications)


Risks and Warnings of Triderm

  • Skin Thinning: Prolonged use of Triderm, especially on sensitive areas such as the face or groin, can cause skin thinning. Use only for the recommended duration and avoid long-term use without consulting your doctor.
  • Systemic Absorption: Although rare, large or long-term use of Triderm can result in systemic absorption of triamcinolone, leading to potential side effects such as adrenal suppression and weight gain.
  • Infection Risk: Using Triderm on infected or broken skin can worsen infections. If signs of infection develop (e.g., increased redness, swelling, or pus), discontinue use and consult your healthcare provider.


Interactions with Triderm

Common Drug Interactions

  • Other topical corticosteroids: Using multiple corticosteroids may increase the risk of side effects like skin thinning or systemic absorption.
  • Topical antibiotics or antifungals: If treating an infection alongside inflammation, consult your healthcare provider on how to apply Triderm with other medications.

Alternatives to Triderm

  • Hydrocortisone 1% cream (OTC): A milder corticosteroid for treating less severe inflammatory skin conditions.
  • Betamethasone (Diprolene): A more potent corticosteroid for severe inflammation and skin conditions.
  • Tacrolimus (Protopic): A non-steroidal alternative for treating eczema and other inflammatory skin conditions.