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Tri-Previfem
Tri-Previfem is a combination oral contraceptive pill used to prevent pregnancy. It contains two active ingredients: ethinyl estradiol (an estrogen) and norgestimate (a progestin), which work together to inhibit ovulation, alter the uterine lining, and thicken cervical mucus to prevent sperm from reaching the egg and fertilization from occurring. Tri-Previfem follows a triphasic dosing schedule, meaning it delivers different hormone levels at three points in the menstrual cycle, which helps more closely mimic the body’s natural hormone fluctuations.
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Frequently Asked Questions
Can Tri-Previfem help with acne?
Yes, Tri-Previfem is FDA-approved for the treatment of moderate acne in females 15 years and older who also desire oral contraception.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more active pills, follow the instructions included with your medication or consult your healthcare provider for guidance.
Can Tri-Previfem cause weight gain?
Some women may experience slight weight gain due to fluid retention or other hormonal changes while using Tri-Previfem, but significant weight changes are uncommon.
Can I stop taking Tri-Previfem whenever I want?
Yes, you can stop taking Tri-Previfem at any time. However, if you stop and do not use another form of contraception, you will be at risk for pregnancy. Consult your healthcare provider for guidance on alternative contraception options.
Does Tri-Previfem protect against sexually transmitted infections (STIs)?
No, Tri-Previfem does not protect against STIs. Condoms should be used to reduce the risk of STIs while on oral contraceptives.
Comprehensive Drug Guide
How Does Tri-Previfem Work?
- Inhibiting ovulation: Prevents the release of an egg from the ovaries.
- Thickening cervical mucus: Makes it more difficult for sperm to travel to the uterus.
- Altering the uterine lining: Reduces the likelihood of a fertilized egg implanting in the uterus.
Common Dosages
- 21 active tablets: with varying doses of estrogen and progestin.
- 7 inactive tablets: placebo pills taken during the last week of the cycle.
Typical Dosing
- Take one active pill daily for 21 days, followed by one inactive pill daily for 7 days.
- Begin a new pack immediately after finishing the 28-day cycle, regardless of whether menstruation has started or ended.
Typical Dosing
FDA Approved Indications
- Contraception (prevention of pregnancy)
- Treatment of moderate acne in females at least 15 years old who desire oral contraception and have begun menstruation
Who Shouldn't Take Tri-Previfem?
- History of blood clots, stroke, or heart attack
- Uncontrolled hypertension
- Known or suspected breast cancer or other estrogen- or progestin-sensitive cancers
- Liver disease
- Pregnancy
Advice From The Pharmacist
- Take Tri-Previfem at the same time every day to ensure consistent hormone levels and maximize contraceptive effectiveness.
- If you miss a pill, follow the instructions provided with your pack or contact your healthcare provider for guidance.
- Tri-Previfem does not protect against sexually transmitted infections (STIs); using condoms is recommended for STI prevention.
- Store the pills in a cool, dry place, and ensure you begin each new pack on time to maintain contraceptive coverage.
Side Effects of Tri-Previfem
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Weight changes
- Mood changes
Uncommon/Severe Side Effects
- Blood clots
- Stroke or heart attack
- High blood pressure
- Liver issues
Risks and Warnings of Tri-Previfem
- Blood Clot Risk: Women over 35 who smoke are at an increased risk of developing blood clots while using Tri-Previfem. It is strongly recommended to stop smoking if you are using this contraceptive.
- Hypertension: Tri-Previfem may cause or worsen high blood pressure. Regular monitoring of blood pressure is recommended while taking this medication.
- Cancer Risk: Prolonged use of combination oral contraceptives may increase the risk of breast cancer or liver tumors in some women.
Interactions with Tri-Previfem
Common Drug Interactions
- Antibiotics: Certain antibiotics, such as rifampin, may reduce the effectiveness of Tri-Previfem.
- Anticonvulsants: Some anticonvulsants may interfere with Tri-Previfem and decrease its contraceptive effectiveness.
- St. John's Wort: This herbal supplement may reduce the effectiveness of hormonal contraceptives.
- HIV medications: Certain HIV treatments may interact with Tri-Previfem, making it less effective.
Alternatives to Tri-Previfem
- Ortho Tri-Cyclen: A similar combination oral contraceptive with the same active ingredients as Tri-Previfem.
- Lo Loestrin Fe: A low-dose estrogen and progestin contraceptive pill.
- Depo-Provera: A progestin-only injectable contraceptive given every three months.
- Intrauterine Device (IUD): A long-acting contraceptive option, available in both hormonal and non-hormonal forms.
