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Tri-Chlor

Tri-Chlor (trichloroacetic acid, or TCA) is a topical medication used to treat various skin conditions, including genital warts, keratosis, and other types of skin lesions. It is a chemical cauterizing agent that works by breaking down proteins in the skin, causing the outer layers to peel away. This promotes new skin growth and helps remove abnormal tissue. Tri-Chlor is commonly used by healthcare providers in medical settings for the treatment of warts and other benign skin growths.



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Frequently Asked Questions

How long does it take for Tri-Chlor to work?
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The treated area will typically start to peel within a few days of application. Full healing may take 1 to 2 weeks, depending on the condition being treated and the depth of the treatment.

Can I use Tri-Chlor at home?
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No, Tri-Chlor should be applied by a healthcare professional in a clinical setting due to the risk of burns, scarring, and improper application.

Does Tri-Chlor cause scarring?
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Scarring can occur if Tri-Chlor is improperly applied or if aftercare instructions are not followed. Keeping the area clean and avoiding picking at the treated skin can help minimize the risk of scarring.

What should I do if I experience severe irritation after using Tri-Chlor?
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Contact your healthcare provider immediately if you experience severe irritation, blistering, or signs of infection, such as redness, swelling, or pus.

Can I use other skin products after a Tri-Chlor treatment?
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Your healthcare provider will advise you on which products are safe to use after treatment. Avoid harsh skincare products, such as retinoids or exfoliants, until your skin has fully healed.

Comprehensive Drug Guide

How Does Tri-Chlor Work?

Trichloroacetic acid works by causing protein coagulation in the treated tissue, leading to the destruction of the superficial layers of the skin. This creates a chemical peel effect, removing the targeted tissue and promoting the growth of new, healthy skin underneath.



Common Dosages

  • Tri-Chlor is available in different concentrations, typically ranging from 50% to 80% trichloroacetic acid solution for topical use.

Typical Dosing

  • Tri-Chlor is applied topically by a healthcare provider, and the concentration and dosing frequency vary depending on the condition being treated.
  • For genital warts, the healthcare provider may apply the solution once every 1 to 2 weeks until the warts are fully resolved.
  • For other skin lesions, the application is usually done during office visits, and patients may require follow-up treatments depending on the response.


Typical Dosing

FDA Approved Indications

  • Treatment of genital warts (caused by human papillomavirus, or HPV)
  • Seborrheic keratosis
  • Actinic keratosis (precancerous skin lesions)
  • Other benign skin growths that require removal


Who Shouldn't Take Tri-Chlor?

  • Allergic reactions to trichloroacetic acid or any components of the solution.
  • Open wounds or active skin infections at the treatment site.
  • Sensitivity to chemical peels or severe dermatologic conditions that could be aggravated by the treatment.


Advice From The Pharmacist

  • Tri-Chlor should only be applied by a healthcare professional in a clinical setting. Do not attempt to use this medication at home unless specifically directed by your healthcare provider.
  • After application, you may experience stinging or burning at the treatment site, which is normal.
  • Avoid picking or scratching the treated area while the skin heals, as this can lead to scarring or infection.
  • Keep the treated area clean and dry, and follow any aftercare instructions given by your healthcare provider.
  • Notify your doctor if you experience any signs of infection, such as increased redness, swelling, or discharge from the treated site.


Side Effects of Tri-Chlor

Common Side Effects

  • Burning or stinging sensation at the application site
  • Redness or swelling
  • Peeling or crusting of the treated skin
  • Temporary discoloration of the skin


Uncommon/Severe Side Effects

  • Severe irritation or blistering
  • Infection at the treatment site
  • Scarring or skin discoloration with improper use or over-application


Risks and Warnings of Tri-Chlor

  • Skin Sensitivity: Tri-Chlor can cause significant irritation and burning if applied inappropriately or in high concentrations. Always follow your healthcare provider’s instructions.
  • Scarring Risk: Improper application or failure to follow aftercare instructions may result in scarring or permanent skin discoloration.
  • Infection: The treated area may be prone to infection if not properly cared for. Keep the area clean and avoid picking at the skin.
  • Eye and Mucous Membrane Exposure: Avoid contact with the eyes, nose, mouth, or mucous membranes, as Tri-Chlor can cause serious irritation. Rinse thoroughly with water if contact occurs and seek medical attention if necessary.


Interactions with Tri-Chlor

Common Drug Interactions

  • Other skin treatments: Avoid using other topical treatments, such as retinoids or salicylic acid, in conjunction with Tri-Chlor unless specifically instructed by your healthcare provider, as these can increase skin irritation.
  • Moisturizers or ointments: Your healthcare provider may recommend certain products to use after treatment to help soothe the skin and promote healing.


Alternatives to Tri-Chlor

  • Salicylic Acid: Another topical treatment for warts and skin keratosis. It works by peeling away the outer layer of skin.
  • Cryotherapy: Freezing of warts or skin growths using liquid nitrogen.
  • Imiquimod (Aldara): A topical cream used for treating genital warts by boosting the immune system's ability to fight the virus.