You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Topical L.E.T.
Topical L.E.T. is a combination anesthetic gel used to provide local anesthesia for minor skin procedures, including laceration repairs and superficial wounds. It contains lidocaine, epinephrine, and tetracaine, which work together to numb the skin, reduce bleeding, and enhance the duration of anesthesia. This topical solution is often used in emergency settings to provide pain relief before suturing or other minor procedures.
Oops! We currently don’t have the pricing information for this drug.
But we're continually improving our service to help you save and earn rebates on your medications. If your drug isn't listed on NiHowdy, you can still present your NiHowdy savings card at the pharmacy. We'll work to secure any eligible rebates for that drug and pass the savings back to you retroactively.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
Frequently Asked Questions
How long does it take for Topical L.E.T. to work?
It usually takes 15 to 30 minutes for Topical L.E.T. to achieve full anesthetic effects. The area will remain numb for a short period after removal.
Can I apply Topical L.E.T. at home?
No, Topical L.E.T. is typically applied in a clinical setting by a healthcare provider due to the risk of overuse or improper application.
What should I do if I experience numbness longer than expected?
Numbness may persist for a short time after the procedure. If numbness lasts longer than expected or spreads beyond the application area, contact your healthcare provider.
Can Topical L.E.T. be used on open wounds?
Topical L.E.T. is intended for minor skin procedures and should not be applied to deep or heavily infected wounds. Always consult with your healthcare provider for proper wound care.
Is Topical L.E.T. safe for children?
Topical L.E.T. can be used in children under medical supervision, but dosing and application should be carefully monitored to prevent overuse or adverse effects.
Comprehensive Drug Guide
How Does Topical L.E.T. Work?
- Lidocaine blocks sodium channels in nerve cells, preventing the transmission of pain signals.
- Tetracaine provides additional local anesthesia by similarly blocking nerve signal transmission.
- Epinephrine constricts blood vessels, reducing bleeding and prolonging the effects of the anesthetics by keeping them localized to the area of application.
Common Dosages
- Topical L.E.T. is typically applied in gel or solution form, and the dosage depends on the area of skin being treated.
Typical Dosing
- Apply a thin layer of L.E.T. gel or solution to the affected area for 15 to 30 minutes prior to a procedure. The exact amount applied and the duration of application depends on the size and location of the wound. A healthcare provider will determine the appropriate dose.
Typical Dosing
FDA Approved Indications
- Local anesthesia before minor skin procedures such as suturing lacerations, skin biopsies, or superficial wound repairs.
Who Shouldn't Take Topical L.E.T.?
- Known hypersensitivity to lidocaine, tetracaine, epinephrine, or other components of the formulation
- Severe heart conditions such as arrhythmias or severe hypertension
- Open wounds with deep tissue involvement or infections
Advice From The Pharmacist
- Do not apply Topical L.E.T. to large areas of the body or for extended periods, as systemic absorption of the anesthetics could occur, increasing the risk of toxicity.
- Avoid contact with the eyes or mucous membranes, as this can cause irritation or systemic effects.
- Topical L.E.T. should only be used under medical supervision, typically in a clinical setting.
Side Effects of Topical L.E.T.
Common Side Effects
- Temporary redness or irritation at the application site
- Mild burning or stinging upon application
- Numbness lasting beyond the expected duration
Uncommon/Severe Side Effects
- Systemic toxicity (dizziness, drowsiness, confusion) from overuse or absorption through large areas
- Allergic reactions (swelling, rash, difficulty breathing)
- Cardiovascular effects (such as irregular heartbeat or increased blood pressure) due to epinephrine
Risks and Warnings of Topical L.E.T.
- Overuse Risk: Excessive application or use on large surface areas can result in systemic toxicity, leading to symptoms like confusion, drowsiness, or cardiovascular issues. Only use as directed by a healthcare provider.
- Vasoconstriction: The epinephrine component may reduce blood flow to the application area, which can prolong healing in some cases, particularly in areas with poor circulation, like fingers or toes.
- Allergic Reactions: Patients with known allergies to local anesthetics or preservatives used in the formulation should avoid using this product.
Interactions with Topical L.E.T.
Common Drug Interactions
- Beta-blockers: Patients taking beta-blockers may experience enhanced effects of epinephrine, potentially causing increased blood pressure or other cardiovascular side effects.
- Other local anesthetics: Combining Topical L.E.T. with other local anesthetics may increase the risk of systemic toxicity.
Alternatives to Topical L.E.T.
- EMLA (lidocaine/prilocaine): A topical anesthetic cream used for numbing the skin before minor procedures.
- Lidocaine patches: Often used to provide localized pain relief without the vasoconstrictive effects of epinephrine.
- Topical lidocaine: Available as a stand-alone local anesthetic without the addition of epinephrine or tetracaine.
