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Spiriva HandiHaler

Spiriva Handihaler is a type of medication known as a long-acting bronchodilator. It's used to control and prevent symptoms (such as wheezing and shortness of breath) caused by ongoing lung diseases like asthma and COPD. Tiotropium does not relieve sudden attacks of breathlessness and it's not used as a 'quick fix'.

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Frequently Asked Questions

How long does it take for Spiriva HandiHaler to start working?
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Patients may begin to notice improvements in breathing within a few hours, but it is important to use it regularly for optimal benefits.

Can I use Spiriva HandiHaler with other inhalers?
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Yes, Spiriva can be used alongside other inhaled medications, but consult your healthcare provider to ensure proper use and timing.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it's close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up.

Is Spiriva HandiHaler safe for long-term use?
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Yes, Spiriva is designed for long-term use in managing COPD and asthma, but regular follow-up with your healthcare provider is important to monitor efficacy and safety.

Can I take Spiriva HandiHaler during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the potential risks and benefits of using Spiriva.

Comprehensive Drug Guide

How Does Spiriva HandiHaler Work?

Tiotropium bromide, the active ingredient in Spiriva, works by blocking the action of acetylcholine at muscarinic receptors in the airways. This inhibition leads to bronchodilation (widening of the airways), which helps alleviate symptoms of bronchospasm associated with COPD and asthma.



What is Spiriva HandiHaler Used For?


Common Dosages

  • Inhalation Capsules: 18 mcg of tiotropium bromide per capsule.

Typical Dosing

  • For COPD: The typical dose is one inhalation of the contents of one capsule (18 mcg) once daily.
  • For asthma: The same dosing of one inhalation once daily is applicable.


Typical Dosing

FDA Approved Indications

  • Maintenance treatment of COPD
  • Maintenance treatment of asthma in patients aged 6 years and older


Pediatric Dosing


Who Shouldn't Take Spiriva HandiHaler?

  • Known hypersensitivity to tiotropium or any components of the formulation.
  • A history of severe allergic reactions to similar medications.


Advice From The Pharmacist

  • Use Spiriva HandiHaler exactly as prescribed by your healthcare provider. Do not exceed the recommended dose.
  • Make sure to use the inhaler correctly. Follow the instructions for preparing and inhaling from the device to ensure proper medication delivery.
  • Avoid getting the medication in your eyes, as it may cause irritation.
  • Keep well-hydrated, as dry mouth can occur with the use of anticholinergic medications.


Side Effects of Spiriva HandiHaler

Common Side Effects

  • Dry mouth
  • Constipation
  • Upper respiratory tract infections
  • Headache


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Worsening of breathing problems or acute bronchospasm


Risks and Warnings of Spiriva HandiHaler

  • Cardiovascular Effects: Caution is advised in patients with a history of cardiovascular disease, as anticholinergic medications can cause palpitations or increased heart rate.
  • Paradoxical Bronchospasm: In rare cases, Spiriva can cause worsening respiratory symptoms. If this occurs, seek medical attention immediately.


Interactions with Spiriva HandiHaler

Common Drug Interactions

  • Other Anticholinergic Medications: Use with caution when combining with other anticholinergic drugs, as this may increase the risk of side effects.
  • Beta-agonist Bronchodilators: Concurrent use is generally safe, but patients should be monitored for increased side effects.


Alternatives to Spiriva HandiHaler

  • Other LAMAs: Such as umeclidinium (Incruse Ellipta) or glycopyrrolate (Seebri Neohaler) may be considered for similar indications.
  • Short-acting bronchodilators: Such as albuterol for acute symptom relief.