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Sorilux
Sorilux (calcipotriene) is a topical medication used primarily for the treatment of plaque psoriasis. It is a synthetic form of vitamin D3 that helps to regulate skin cell production and reduce inflammation. Sorilux is effective in reducing the scaling and thickness of psoriasis plaques, promoting clearer skin in patients suffering from this chronic condition.
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Frequently Asked Questions
How long does it take to see results from Sorilux?
Patients may begin to notice improvements within a few weeks of consistent use, but optimal results can take several weeks to months.
Can I use Sorilux on sensitive areas, like the face?
Consult your healthcare provider before applying Sorilux to sensitive areas, as specific guidance may be needed for those regions.
What should I do if I miss a dose of Sorilux?
If you miss a dose, apply it as soon as you remember. If it’s close to your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply extra to make up for a missed dose.
Is it safe to use Sorilux during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding, as safety during these periods has not been fully established.
Can I use Sorilux with other psoriasis treatments?
Yes, but always consult your healthcare provider before combining treatments to avoid irritation and ensure optimal management of your condition.
Comprehensive Drug Guide
How Does Sorilux Work?
Sorilux works by binding to vitamin D receptors in the skin, which leads to a reduction in the proliferation of keratinocytes (skin cells) and promotes the differentiation of these cells. This action helps to normalize skin cell turnover, reducing the formation of thick, scaly patches characteristic of psoriasis.
Common Dosages
- Topical Foam: Typically in a concentration of 0.005% calcipotriene.
- Topical Solution: Available in a similar concentration for targeted application.
Typical Dosing
- For plaque psoriasis: Apply a thin layer of Sorilux to the affected areas once daily, preferably at the same time each day. It can be used for a maximum of 8 weeks unless directed otherwise by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Treatment of plaque psoriasis in adults and children aged 12 years and older.
Who Shouldn't Take Sorilux?
- Known hypersensitivity to calcipotriene or any components of the formulation.
- Conditions that lead to hypercalcemia (elevated levels of calcium in the blood).
Advice From The Pharmacist
- Apply Sorilux only to the affected areas and avoid contact with the eyes, mouth, and other mucous membranes.
- Wash hands after application to avoid accidental transfer to other areas or individuals.
- Monitor skin for any signs of irritation or worsening condition, and contact your healthcare provider if these occur.
- Avoid using Sorilux with other topical treatments for psoriasis unless directed by your healthcare provider.
Side Effects of Sorilux
Common Side Effects
- Skin irritation
- Burning sensation at the application site
- Dryness or peeling of the skin
Uncommon/Severe Side Effects
- Skin irritation
- Burning sensation at the application site
- Dryness or peeling of the skin
Risks and Warnings of Sorilux
- Hypercalcemia Risk: Prolonged use or overapplication can increase the risk of elevated calcium levels. Regular monitoring may be necessary, especially in patients with renal impairment.
- Sun Exposure: Limit excessive sun exposure while using Sorilux, as it may increase sensitivity to sunlight.
Interactions with Sorilux
Common Drug Interactions
- Other Topical Treatments: Use with caution if applying other topical products simultaneously, as this may increase skin irritation.
- Calcium Supplements: Discuss with your healthcare provider if you are taking calcium or vitamin D supplements to avoid potential interactions.
Alternatives to Sorilux
- Other Topical Treatments: Alternatives include corticosteroids, retinoids, or other vitamin D analogs such as calcitriol.
- Phototherapy: Light therapy can also be effective for managing psoriasis.
