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Skelaxin
Skelaxin, the brand name for metaxalone, is a muscle relaxant used to treat muscle spasms, pain, and discomfort caused by acute musculoskeletal conditions such as strains, sprains, and other injuries. Metaxalone works by acting on the central nervous system (CNS) to relax the muscles, but it does not directly relax skeletal muscles. Skelaxin is typically used in combination with rest, physical therapy, and other treatments to relieve discomfort associated with musculoskeletal conditions.
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Frequently Asked Questions
How long does it take for Skelaxin to start working?
Skelaxin typically starts to work within 1 hour after taking the dose, providing relief from muscle spasms and pain.
Can I take Skelaxin with pain medications?
Skelaxin can often be taken alongside over-the-counter pain medications like acetaminophen or ibuprofen. However, you should avoid combining it with opioids or other sedatives without consulting your healthcare provider.
Is Skelaxin addictive?
Skelaxin has a low potential for abuse compared to other muscle relaxants like carisoprodol (Soma). It is not classified as a controlled substance.
Can Skelaxin be used long-term?
Skelaxin is generally used for short-term relief of acute musculoskeletal pain and spasms. Long-term use is not typically recommended due to the risk of side effects such as drowsiness, dizziness, and liver problems.
What should I do if I experience side effects from Skelaxin?
If you experience mild side effects like drowsiness or dizziness, it is usually safe to continue the medication, but avoid activities that require alertness. If you experience serious side effects like jaundice, rash, or difficulty breathing, seek medical attention immediately.
Comprehensive Drug Guide
How Does Skelaxin Work?
Skelaxin (metaxalone) works by acting on the central nervous system (CNS), but its exact mechanism of action is not fully understood. It is believed to inhibit nerve impulses or pain sensations sent to the brain, thereby providing relief from muscle spasms and discomfort. Unlike some other muscle relaxants, Skelaxin does not directly affect skeletal muscles.
Common Dosages
- 800 mg tablets
Typical Dosing
- The typical adult dosage is 800 mg three to four times a day, depending on the severity of the condition and the patient's response to treatment.
- Skelaxin should be taken with or without food, but taking it with food may help reduce gastrointestinal discomfort.
Typical Dosing
FDA Approved Indications
- Relief of discomfort associated with acute, painful musculoskeletal conditions.
Who Shouldn't Take Skelaxin?
- Known hypersensitivity to metaxalone or any components of the formulation.
- Severe liver impairment, as metaxalone is metabolized by the liver, and impaired liver function may lead to an increased risk of side effects.
- History of drug-induced hemolytic or other anemias.
Advice From The Pharmacist
- Take Skelaxin as directed by your healthcare provider. It can be taken with or without food, but taking it with food may help reduce stomach upset.
- Avoid alcohol while taking Skelaxin, as it can increase the sedative effects and cause increased drowsiness or dizziness.
- Skelaxin may cause drowsiness or dizziness. Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
- If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and take the next one at the regular time. Do not double up on doses.
Side Effects of Skelaxin
Common Side Effects
- Drowsiness
- Dizziness
- Nausea
- Vomiting
- Headache
- Irritability
Uncommon/Severe Side Effects
- Liver problems: Symptoms such as yellowing of the skin or eyes (jaundice), dark urine, or stomach pain.
- Allergic reactions: Rash, itching, swelling, or difficulty breathing.
- Blood disorders: Metaxalone has been associated with hemolytic anemia and other blood-related issues in rare cases.
Risks and Warnings of Skelaxin
- Drowsiness and dizziness: Skelaxin may cause significant drowsiness and dizziness. Patients should avoid driving or operating heavy machinery until they know how the drug affects them.
- Liver impairment: Skelaxin is metabolized by the liver, and patients with liver disease should use this medication cautiously or avoid it. Regular liver function tests may be necessary.
- Alcohol and CNS depressants: The sedative effects of Skelaxin may be enhanced by alcohol or other CNS depressants (e.g., benzodiazepines). Patients should avoid consuming these substances while taking Skelaxin.
Interactions with Skelaxin
Common Drug Interactions
- Alcohol and CNS depressants: Combining Skelaxin with alcohol or other CNS depressants (e.g., sedatives, benzodiazepines, or opioids) can increase the risk of drowsiness, dizziness, and respiratory depression.
- Antidepressants or antianxiety medications: Medications like SSRIs, SNRIs, or benzodiazepines may enhance the sedative effects of Skelaxin.
- Blood thinners: Patients taking warfarin or other anticoagulants should inform their healthcare provider, as metaxalone may increase the risk of bleeding.
Alternatives to Skelaxin
- Cyclobenzaprine (Flexeril): Another centrally acting muscle relaxant used to treat muscle spasms.
- Methocarbamol (Robaxin): A muscle relaxant commonly used for musculoskeletal pain and spasms.
- Baclofen: A muscle relaxant that works on the central nervous system, often used for spasticity in neurological conditions.
- Carisoprodol (Soma): Another muscle relaxant used to treat musculoskeletal pain and spasms.
