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Sila III

Sila III is a combination medication that contains silicone oil and dexamethasone. It is primarily used in ophthalmic applications to manage conditions such as intraocular inflammation and to facilitate surgical procedures in the eye. This combination helps to reduce inflammation and provides a protective barrier, improving patient comfort during eye treatments.


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Frequently Asked Questions

How quickly does Sila III work?
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Patients may begin to notice improvements in symptoms within a few hours to days after starting treatment.

Can I use Sila III with contact lenses?
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Consult your healthcare provider regarding the use of Sila III while wearing contact lenses, as it may be advised to remove them during treatment.

What should I do if I miss a dose?
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If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is Sila III safe for long-term use?
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Long-term use should be monitored by a healthcare provider, as it may increase the risk of side effects such as elevated intraocular pressure.

Can Sila III be used during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding, as the safety of Sila III during these periods should be evaluated on a case-by-case basis.

Comprehensive Drug Guide

How Does Sila III Work?

The silicone oil in Sila III provides a lubricating effect that helps protect the surface of the eye, while dexamethasone, a corticosteroid, works to reduce inflammation by suppressing the immune response. This dual action helps alleviate symptoms associated with inflammatory eye conditions and aids in the recovery process after surgical procedures.


Common Dosages

  • Ophthalmic Solution/Emulsion: The specific concentration may vary based on the formulation, often containing a defined percentage of silicone oil and dexamethasone.

Typical Dosing

  • For intraocular inflammation: The typical dosage is one to two drops of Sila III in the affected eye(s) four times daily, or as directed by a healthcare provider. The dosing frequency may be adjusted based on the severity of the condition.

Typical Dosing

FDA Approved Indications

  • Management of intraocular inflammation
  • Use during cataract surgery or other ocular procedures to enhance patient comfort and reduce inflammation

Who Shouldn't Take Sila III?

  • Known hypersensitivity to dexamethasone, silicone oil, or any components of the formulation.
  • Active viral, fungal, or mycobacterial infections of the eye.

Advice From The Pharmacist

  • Use Sila III exactly as prescribed by your healthcare provider. Follow the instructions regarding the number of drops and frequency of use.
  • Avoid touching the dropper tip to any surface, including the eye, to prevent contamination.
  • Monitor for any signs of irritation or adverse reactions, and contact your healthcare provider if symptoms worsen.

Side Effects of Sila III

Common Side Effects

  • Burning or stinging upon instillation
  • Blurred vision
  • Dry eyes or increased tear production

Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Increased intraocular pressure or glaucoma with prolonged use

Risks and Warnings of Sila III

  • Infection Risk: Corticosteroids can suppress the immune response, potentially increasing the risk of infections. Patients should be monitored for any signs of infection.
  • Intraocular Pressure: Prolonged use of corticosteroids can lead to increased intraocular pressure, which may require monitoring in susceptible individuals.

Interactions with Sila III

Common Drug Interactions

  • Other Ophthalmic Medications: Consult your healthcare provider before using other eye drops or medications simultaneously to avoid interactions and ensure efficacy.

Alternatives to Sila III

  • Other Corticosteroids: Alternatives may include prednisolone acetate or fluorometholone for managing intraocular inflammation.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Such as ketorolac, can be used for inflammation control in certain cases.