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SfRowasa
SfRowasa (mesalamine) is a topical 5-aminosalicylic acid (5-ASA) agent used primarily for the treatment of ulcerative colitis and proctitis. It works by reducing inflammation in the intestinal lining, thereby alleviating symptoms such as diarrhea, rectal bleeding, and abdominal pain associated with inflammatory bowel diseases. SfRowasa is typically administered as a rectal enema, delivering medication directly to the inflamed area.
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Frequently Asked Questions
How long does it take for SfRowasa to work?
Patients may begin to notice improvements in their symptoms within a few days to a few weeks of starting treatment.
Can I use SfRowasa while pregnant or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the potential risks and benefits of using SfRowasa.
What should I do if I miss a dose of SfRowasa?
If you miss a dose, use it as soon as you remember. If it’s close to the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can I take other medications while using SfRowasa?
Always inform your healthcare provider of all medications you are taking to avoid potential interactions and ensure safe use.
Are there any dietary restrictions while taking SfRowasa?
There are no specific dietary restrictions, but maintaining a balanced diet and avoiding trigger foods may help manage ulcerative colitis symptoms. Always follow your healthcare provider's dietary recommendations.
Comprehensive Drug Guide
How Does SfRowasa Work?
Mesalamine, the active ingredient in SfRowasa, exerts its anti-inflammatory effects locally in the gastrointestinal tract. It is thought to inhibit the production of inflammatory mediators and free radicals, thereby reducing the inflammatory response in the colon and rectum. This localized action helps improve the symptoms of ulcerative colitis and promotes healing of the intestinal lining.
Common Dosages
- Rectal Enema: Each enema typically contains 4 grams of mesalamine in 60 mL of solution.
Typical Dosing
- For active ulcerative colitis: The typical dose is one 60 mL enema administered once daily, preferably at bedtime. Treatment duration may vary based on individual response and clinical guidelines.
Typical Dosing
FDA Approved Indications
- Treatment of active ulcerative colitis and proctitis.
- Maintenance of remission in patients with ulcerative colitis.
Who Shouldn't Take SfRowasa?
- Known hypersensitivity to mesalamine or any components of the formulation.
- Severe renal impairment or history of hypersensitivity to salicylates.
Advice From The Pharmacist
- Administer SfRowasa as directed by your healthcare provider. Follow the instructions for proper use of the enema for optimal delivery of the medication.
- Retain the enema solution for at least 30 minutes or as directed to maximize effectiveness.
- Monitor for any signs of worsening symptoms or side effects, such as abdominal pain, diarrhea, or allergic reactions.
Side Effects of SfRowasa
Common Side Effects
- Abdominal pain or cramping
- Diarrhea
- Nausea
- Headache
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Pancreatitis (symptoms include severe abdominal pain, nausea)
- Kidney problems (elevated creatinine levels)
Risks and Warnings of SfRowasa
- Renal Function: Patients should be monitored for renal function during treatment, especially those with pre-existing kidney issues.
- Allergic Reactions: Be vigilant for signs of allergic reactions, particularly during the first few weeks of treatment.
Interactions with SfRowasa
Common Drug Interactions
- Other Medications: Inform your healthcare provider of all medications you are taking, including over-the-counter drugs, as there may be potential interactions.
Alternatives to SfRowasa
- Other 5-ASA Products: Alternatives include mesalamine in oral form or other rectal formulations, such as Rowasa (another mesalamine product).
- Corticosteroids: May be used for more severe cases of ulcerative colitis to control inflammation.
