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Reyvow
Reyvow (lasmiditan) is a serotonin (5-HT) receptor agonist specifically indicated for the acute treatment of migraine in adults. It is a novel medication that targets the 5-HT_1F receptor, providing a different mechanism of action compared to traditional triptans. Reyvow is designed to relieve migraine attacks with a reduced risk of vasoconstriction, making it a potential option for patients who may not respond well to or have contraindications for other migraine treatments.
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Frequently Asked Questions
How quickly does Reyvow start to work?
Reyvow typically begins to relieve migraine symptoms within 1 to 2 hours after taking the medication.
How quickly does Reyvow start to work?
Reyvow typically begins to relieve migraine symptoms within 1 to 2 hours after taking the medication.
Can I stop taking Reyvow suddenly?
It is generally safe to stop Reyvow without tapering, but consult your healthcare provider if you have concerns about your migraine management.
Are there any specific dietary restrictions while taking Reyvow?
There are no specific dietary restrictions, but maintaining a balanced diet and hydration can support overall health.
What should I do if I miss a dose of Reyvow?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Reyvow is not intended for routine daily use; take it only as needed for migraine attacks.
Is Reyvow safe for long-term use?
Reyvow is intended for the acute treatment of migraines and can be used as needed. Long-term management of migraine should be discussed with your healthcare provider to determine the most appropriate treatment plan.
Comprehensive Drug Guide
How Does Reyvow Work?
Lasmiditan acts as a selective agonist for the 5-HT_1F receptor, which is involved in the modulation of pain signaling in the brain. By activating this receptor, Reyvow reduces the transmission of pain signals related to migraine headaches without causing significant vasoconstriction of cranial blood vessels, which is a common side effect of traditional migraine treatments.
Common Dosages
- Tablets: 50 mg and 100 mg
Typical Dosing
- The recommended starting dose for treating a migraine is 100 mg taken orally as soon as possible after the onset of a migraine attack. If needed, a second dose of 100 mg may be taken after 24 hours, but the total daily dose should not exceed 200 mg.
Typical Dosing
FDA Approved Indications
- Acute treatment of migraine with or without aura in adults.
Who Shouldn't Take Reyvow?
- Known hypersensitivity to lasmiditan or any of its components
- History of serious cardiovascular disease (e.g., stroke, transient ischemic attack)
Advice From The Pharmacist
- Take Reyvow exactly as prescribed, and it is recommended to take it as soon as possible after the onset of a migraine.
- Avoid driving or operating heavy machinery until you know how Reyvow affects you, as it can cause dizziness or sedation.
- Inform your healthcare provider about any other medications you are taking to avoid potential interactions.
Side Effects of Reyvow
Common Side Effects
- Dizziness
- Fatigue
- Drowsiness or sedation
- Nausea
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Symptoms of serotonin syndrome, which can include confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, and excessive sweating.
Risks and Warnings of Reyvow
- Sedation and Dizziness: Reyvow can cause sedation; patients should be cautioned against activities requiring alertness until they understand how the medication affects them.
- Serotonin Syndrome: Patients should be monitored for symptoms of serotonin syndrome, especially when taking other serotonergic medications.
- Cardiovascular Monitoring: Caution is advised in patients with a history of cardiovascular disease due to potential cardiovascular effects.
Interactions with Reyvow
Common Drug Interactions
- CNS Depressants: The sedative effects of Reyvow may be enhanced when taken with alcohol or other CNS depressants.
- Serotonergic Drugs: Caution is advised when Reyvow is used with other serotonergic medications, as this may increase the risk of serotonin syndrome.
Alternatives to Reyvow
- Triptans: Such as sumatriptan or rizatriptan, which are commonly used for the acute treatment of migraines.
- Other Migraine Treatments: Including NSAIDs, antiemetics, or preventive medications like beta-blockers or anticonvulsants.
