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Relenza Diskhaler
Relenza Diskhaler (zanamivir) is an antiviral medication used for the treatment and prevention of influenza (the flu) in patients aged 7 years and older. It is effective against both influenza A and B viruses. Relenza works by inhibiting the neuraminidase enzyme, which is essential for the viral replication and release process, thereby reducing the severity and duration of flu symptoms.
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Frequently Asked Questions
How quickly does Relenza Diskhaler start to work?
Patients may start to feel relief from symptoms within 24 to 48 hours of initiating treatment, but it is most effective when taken as soon as symptoms begin.
Can I stop taking Relenza suddenly?
It is important to complete the full course of treatment as prescribed, even if you start feeling better before finishing the medication.
Are there any specific dietary restrictions while using Relenza?
There are no specific dietary restrictions while using Relenza Diskhaler.
What should I do if I miss a dose of Relenza?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Relenza safe for long-term use?
Relenza is intended for short-term use during influenza outbreaks. Long-term use is not typically recommended, and ongoing treatment should be discussed with a healthcare provider to assess necessity and safety.
Comprehensive Drug Guide
How Does Relenza Diskhaler Work?
Zanamivir works by selectively inhibiting the neuraminidase enzyme found on the surface of influenza viruses. This inhibition prevents the release of newly formed viral particles from infected cells, thereby reducing the spread of the virus within the respiratory tract and minimizing the impact of the infection on the host.
Common Dosages
- Powder for inhalation: Each blister contains 5 mg of zanamivir.
Typical Dosing
- For treatment of influenza: The recommended dose is 10 mg (2 inhalations) twice daily for 5 days.
- For prophylaxis: The recommended dose is 10 mg (2 inhalations) once daily for 10 days following exposure during an outbreak.
Typical Dosing
FDA Approved Indications
- Treatment of acute influenza in patients aged 7 years and older who have been symptomatic for no more than 2 days.
- Prophylaxis of influenza in individuals aged 5 years and older during outbreaks or after exposure.
Who Shouldn't Take Relenza Diskhaler?
- Known hypersensitivity to zanamivir or any components of the formulation.
- A history of severe asthma or other chronic respiratory conditions that may be exacerbated by inhalation.
Advice From The Pharmacist
- Instruct patients on the proper use of the Diskhaler device, emphasizing the importance of inhalation technique to ensure effective delivery of the medication.
- Advise patients to begin treatment as soon as possible after the onset of flu symptoms for optimal effectiveness.
- Discuss potential side effects, including respiratory symptoms, and encourage patients to report any unusual reactions or worsening of respiratory conditions.
Side Effects of Relenza Diskhaler
Common Side Effects
- Headache
- Throat discomfort
- Cough
- Nasal congestion
- Nausea
Uncommon/Severe Side Effects
- Bronchospasm or worsening of asthma symptoms
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
Risks and Warnings of Relenza Diskhaler
- Respiratory Issues: Patients with a history of asthma or chronic obstructive pulmonary disease (COPD) should be closely monitored during treatment, as Relenza can cause bronchospasm.
- Allergic Reactions: Patients should be educated about the potential for serious allergic reactions and instructed to seek medical attention if they experience any symptoms of hypersensitivity.
Interactions with Relenza Diskhaler
Common Drug Interactions
- Other Respiratory Medications: Patients should inform their healthcare provider of all medications they are taking, especially other inhaled medications or respiratory therapies, to avoid potential interactions.
Alternatives to Relenza Diskhaler
- Other Antiviral Medications: Alternatives for the treatment of influenza include oseltamivir (Tamiflu) and peramivir, which may be considered based on patient-specific factors and drug availability.