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Recedo
Recedo (ondansetron) is an antiemetic medication used primarily to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking the actions of serotonin, a neurotransmitter that can trigger nausea and vomiting. Recedo is effective in reducing the severity of these symptoms, helping patients tolerate their treatment better.
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Frequently Asked Questions
How quickly does Recedo start to work?
Patients may start to feel relief from nausea and vomiting within 30 minutes after taking ondansetron, with peak effects occurring around 1 to 2 hours post-administration.
Can I stop taking Recedo suddenly
If you have been using ondansetron for a prolonged period, consult your healthcare provider before discontinuing, particularly if you have ongoing nausea or vomiting.
Are there any specific dietary restrictions while using Recedo?
There are no specific dietary restrictions, but patients may find that eating small, frequent meals can help manage nausea.
What should I do if I miss a dose of Recedo?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is Recedo safe for long-term use?
Recedo is generally used for short-term management of nausea and vomiting, particularly associated with chemotherapy or surgery. Long-term use should be monitored by a healthcare provider to assess ongoing need and any potential side effects.
Comprehensive Drug Guide
How Does Recedo Work?
Ondansetron works by selectively blocking serotonin receptors (5-HT3 receptors) in the central nervous system and gastrointestinal tract. By inhibiting the action of serotonin, it prevents the activation of pathways that lead to nausea and vomiting, particularly those associated with chemotherapy and radiation.
Common Dosages
- Oral tablets: Common strengths include 4 mg and 8 mg.
- Orally disintegrating tablets: 4 mg and 8 mg.
- Injectable solution: 4 mg/2 mL.
Typical Dosing
- For chemotherapy-induced nausea and vomiting: The usual dose is 8 mg taken orally 30 minutes before the start of chemotherapy, followed by 8 mg every 12 hours for up to 2 days.
- For postoperative nausea and vomiting: The recommended dose is 4 mg administered intravenously 30 minutes before the end of surgery.
Typical Dosing
FDA Approved Indications
- Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy.
- Prevention of postoperative nausea and vomiting.
- Prevention of nausea and vomiting associated with moderate emetogenic chemotherapy.
Who Shouldn't Take Recedo?
- Known hypersensitivity to ondansetron or any components of the formulation.
- Concomitant use of apomorphine, as it may lead to severe hypotension and loss of consciousness.
Advice From The Pharmacist
- Instruct patients to take Recedo as prescribed, and to ensure they take the first dose at the appropriate time relative to chemotherapy or surgery.
- Advise patients that ondansetron may cause constipation; drinking plenty of fluids and maintaining dietary fiber may help mitigate this side effect.
- Discuss potential side effects and encourage patients to report any severe headaches, dizziness, or signs of allergic reactions.
Side Effects of Recedo
Common Side Effects
- Headache
- Constipation
- Dizziness
- Fatigue
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- QT prolongation leading to arrhythmias (increased risk in patients with pre-existing heart conditions).
Risks and Warnings of Recedo
- Cardiac Effects: Ondansetron may cause QT prolongation, and caution should be taken in patients with a history of arrhythmias or those on medications that can also prolong the QT interval.
- Serotonin Syndrome: Though rare, ondansetron has been associated with serotonin syndrome, especially when used in conjunction with other serotonergic agents.
Interactions with Recedo
Common Drug Interactions
- Other Medications: Patients should inform their healthcare provider about all medications they are taking, especially those affecting serotonin levels (such as SSRIs or SNRIs) or those that prolong the QT interval.
Alternatives to Recedo
- Other Anti-nausea Medications: Alternatives may include other 5-HT3 receptor antagonists like granisetron or palonosetron, or non-pharmacologic measures such as acupressure or dietary modifications.
