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ProCentra

ProCentra (dexmethylphenidate hydrochloride) is a central nervous system stimulant primarily used for the treatment of attention-deficit hyperactivity disorder (ADHD) in children and adults. It is the d-enantiomer of methylphenidate and works by enhancing the levels of certain neurotransmitters in the brain, which helps improve focus, attention, and impulse control.

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Frequently Asked Questions

How quickly does ProCentra start to work?
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Patients may begin to notice improvements in ADHD symptoms within 30 to 60 minutes after taking ProCentra, with peak effects typically occurring within 1 to 2 hours.

Can I stop taking ProCentra suddenly?
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It is not advisable to stop taking ProCentra abruptly without consulting your healthcare provider, as this can lead to withdrawal symptoms. A gradual tapering of the dose may be recommended.

Are there any specific dietary restrictions while taking ProCentra?
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There are no specific dietary restrictions; however, maintaining a balanced diet is important, as decreased appetite can be a side effect.

What should I do if I miss a dose of ProCentra?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Is ProCentra safe for long-term use?
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ProCentra can be used long-term under medical supervision, but regular follow-ups are essential to monitor effectiveness and any potential side effects, particularly concerning cardiovascular health and growth in children.

Comprehensive Drug Guide

How Does ProCentra Work?

Dexmethylphenidate works primarily by inhibiting the reuptake of norepinephrine and dopamine in the brain, which increases the availability of these neurotransmitters in the synaptic cleft. This action is believed to enhance attention and focus while reducing impulsivity and hyperactivity in individuals with ADHD.

Common Dosages

  • Oral solution: 5 mg/5 mL.

Typical Dosing

  • The usual starting dose for children and adults is 2.5 mg taken orally once daily, which may be adjusted based on the individual's response. The maximum recommended dose is 20 mg per day.

Typical Dosing

FDA Approved Indications

  • Treatment of attention-deficit hyperactivity disorder (ADHD) in children aged 6 years and older, as well as in adults.

Who Shouldn't Take ProCentra?

  • Known hypersensitivity to dexmethylphenidate or any components of the formulation.
  • A history of serious cardiovascular problems, such as heart disease or hypertension.
  • Glaucoma or a history of drug abuse.

Advice From The Pharmacist

  • Instruct patients to take ProCentra exactly as prescribed and to not increase the dose without consulting their healthcare provider.
  • Advise patients about the potential for insomnia and to avoid taking the medication too close to bedtime.
  • Discuss the importance of monitoring for side effects, including changes in mood, increased heart rate, or blood pressure, and encourage them to report any concerns to their healthcare provider.

Side Effects of ProCentra

Common Side Effects

  • Decreased appetite
  • Insomnia
  • Dry mouth
  • Anxiety
  • Increased heart rate

Uncommon/Severe Side Effects

  • Cardiovascular events (such as heart attack or stroke)
  • Psychiatric symptoms (such as new or worsening anxiety, agitation, or mania)

Risks and Warnings of ProCentra

  • Cardiovascular Risk: Patients with a history of heart problems should be closely monitored for any cardiovascular symptoms, and a thorough medical evaluation is recommended before initiating treatment.
  • Potential for Abuse: Because ProCentra is a controlled substance, it has the potential for abuse and dependence; patients should be educated about this risk.

Interactions with ProCentra

Common Drug Interactions

  • Other Stimulants: Caution should be exercised when using ProCentra with other stimulant medications or medications that increase blood pressure or heart rate.
  • Monoamine Oxidase Inhibitors (MAOIs): Concurrent use with MAOIs should be avoided, as it may lead to serious cardiovascular complications.

Alternatives to ProCentra

  • Other ADHD Medications: Alternatives include other stimulant medications (such as methylphenidate or amphetamine-based products) and non-stimulant options (such as atomoxetine or guanfacine), which may be considered based on individual patient needs.