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Primidone
Primidone is an anticonvulsant or antiseizure medication, often used to control and manage seizures. Some common side effects include tiredness, loss of appetite, and nausea. Your healthcare provider will weigh these potential drawbacks against the benefit of seizure control.
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Frequently Asked Questions
Are there any dietary restrictions while taking Primidone?
There aren't any specific dietary restrictions, but maintaining a balanced, nutritious diet is always beneficial. Grapefruit is known to interact with this drug, so best to avoid it.
Can I consume alcohol while taking Primidone?
No, it's best not to as alcohol can enhance the sleepiness side effect caused by Primidone, making it unsafe to operate machinery or drive. It's also potentially harmful to your liver.
Can I just stop taking Primidone when I feel better?
No, the treatment process for seizures requires a gradual reduction of medication under your healthcare provider's guidance. Abrupt cessation of the drug can lead to the return of seizures.
How will I know if the medication is working?
The best way is to keep track of the frequency of seizures along with their intensity. Maintain regular visits to your doctor to assess your progress and adjust medication if needed.
Comprehensive Drug Guide
How Does Primidone Work?
Primidone positively alters certain electrical activities in the brain, thus helping to reduce or control seizures.
What is Primidone Used For?
FDA indications: Primidone is primarily used to control convulsions in conditions like epilepsy.
Offlabel uses: Sometimes, healthcare providers use Primidone for treating essential tremors.
Common Dosages
Tablets: 50mg, 250mg
Typical Dosing
FDA Approved Indications
- For epilepsy treatment: Ranges from 100 to 250 mg per day, gradually increased to a maintenance dose of 250 mg three to four times daily.
Who Shouldn't Take Primidone?
- Have porphyria, a group of genetic disorders affecting the nervous system and skin.
- Have asthma or other respiratory diseases.
- Have liver disease.
- Are allergic to other barbiturates.
- Are pregnant, or planning to become pregnant (unless with specific advice from a healthcare provider).
Advice From The Pharmacist
- Maintain regular followups with your doctor to monitor your responses to the medication.
- Do not stop taking Primidone without discussing it with your doctor ? sudden cessation can trigger more seizures.
- Be mindful of some common side effects: drowsiness, nausea, and loss of appetite.
- Try to take Primidone with food, especially if you experience an upset stomach.
- If you start to experience more severe side effects, like rash, itching, swelling of the face, severe dizziness, etc., seek medical help immediately.
Side Effects of Primidone
Common Side Effects
- Common side effects include fatigue, nausea, and loss of appetite.
Uncommon/Severe Side Effects
- Rare side effects: Skin rash, pruritus, or fever might occur.
- Severe side effects: Should you experience signs of severe mental/mood changes, slurred speech, clumsiness, or trouble walking, contact your healthcare provider.
Risks and Warnings of Primidone
- Ron to your doctor if you have a history of porphyria, liver disease, or other respiratory conditions like asthma.
- Because Primidone can make you drowsy, avoid any activities that require alertness like driving or operating machinery.
- Be aware that sudden cessation of Primidone can lead to the return of seizures. Always follow your doctor's guidelines regarding dose adjustments and discontinuation.
Interactions with Primidone
Common Drug Interactions
- Warfarin
- Phenytoin
- Theophylline
- Alcohol
Alternatives to Primidone
- Phenytoin
- Valproate
- Levetiracetam
- Lamotrigine
- Gabapentin
- Carbamazepine
