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Pramoxine-HC
Pramoxine-HC is a topical medication that combines pramoxine hydrochloride, a local anesthetic, with hydrocortisone, a corticosteroid. This combination is used primarily for the relief of itching, pain, and inflammation associated with various skin conditions, such as hemorrhoids, eczema, and other minor skin irritations. The pramoxine provides immediate numbing relief, while hydrocortisone reduces inflammation and swelling.
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Frequently Asked Questions
How quickly does Pramoxine-HC start to work?
Patients typically experience relief from itching and pain within minutes of application.
Can I use Pramoxine-HC on broken skin?
It is not recommended to use Pramoxine-HC on broken or severely damaged skin unless directed by a healthcare provider.
Are there any specific precautions I should take while using Pramoxine-HC?
Avoid using it near the eyes or on mucous membranes. Wash hands thoroughly after application to prevent unintentional contact.
What should I do if I experience irritation from Pramoxine-HC?
If irritation or an allergic reaction occurs, discontinue use immediately and consult your healthcare provider.
Is Pramoxine-HC safe for long-term use?
Pramoxine-HC is generally intended for short-term use. Prolonged application should be discussed with a healthcare provider to assess risks and benefits.
Comprehensive Drug Guide
How Does Pramoxine-HC Work?
Pramoxine works by blocking nerve signals in the skin, providing localized pain relief by numbing the area. Hydrocortisone reduces inflammation and immune response in the affected area, helping to alleviate redness, swelling, and discomfort. Together, these components provide dual relief from itching and pain.
Common Dosages
- Topical cream or lotion: Common concentrations include pramoxine 1% and hydrocortisone 1%.
Typical Dosing
- Apply a thin layer of Pramoxine-HC to the affected area 2 to 4 times daily as needed. It is important to follow the specific dosing instructions provided by your healthcare provider.
Typical Dosing
FDA Approved Indications
- Temporary relief of itching and pain associated with hemorrhoids and other skin conditions.
Who Shouldn't Take Pramoxine-HC?
- Known hypersensitivity to pramoxine, hydrocortisone, or any components of the formulation.
- Bacterial, fungal, or viral skin infections (unless directed by a healthcare provider).
Advice From The Pharmacist
- Instruct patients to apply Pramoxine-HC only to clean, dry skin, and avoid contact with eyes, mouth, or mucous membranes.
- Advise patients to wash their hands before and after applying the cream to prevent irritation or spreading infection.
- Monitor for any adverse reactions, including increased irritation or allergic reactions, and discontinue use if these occur.
Side Effects of Pramoxine-HC
Common Side Effects
- Localized irritation or redness
- Burning or stinging sensation at the application site
- Dryness or peeling of the skin
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing)
- Signs of infection in the treated area
Risks and Warnings of Pramoxine-HC
- Skin Irritation: Prolonged use or application to large areas may increase the risk of skin irritation or systemic absorption of hydrocortisone.
- Allergic Reactions: Patients should be monitored for signs of hypersensitivity, especially during initial use.
Interactions with Pramoxine-HC
Common Drug Interactions
- Other Topical Medications: Use with caution, as combining Pramoxine-HC with other topical agents may increase the risk of skin irritation or reduce effectiveness.
Alternatives to Pramoxine-HC
- Other Topical Anesthetics: Such as lidocaine or benzocaine for similar pain relief.
- Topical Corticosteroids: May be used for inflammation without the anesthetic component.
