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Posaconazole
Posaconazole is an antifungal medicine that fights certain types of fungus. Fight off fungal infections, such as Aspergillosis, Candidemia, and certain types of Mucormycosis with Posaconazole! It is generally welltolerated but may have side effects such as diarrhea, nausea, and fever, among others. Your doctor will ensure the benefits of using Posaconazole far outweigh any minor inconveniences.
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Frequently Asked Questions
Are there any foods or drinks I should avoid while on Posaconazole?
Avoid grapefruit and grapefruit juice while on this medication as they can increase the amount of Posaconazole in your blood. Always take this medication with a full meal for better absorption.
Can I just stop taking Posaconazole once my symptoms are gone?
No, the entire course of the medication should be completed, even if your symptoms improve before the course is completed. Stopping the medication too soon may allow the fungus to continue to grow, leading to a relapse of the infection." "
Can I take Posaconazole with other medications?
Always consult your healthcare provider before starting any new medication. Posaconazole can interact with other drugs, altering the way the medicine works or increasing your risk for side effects.
What should I do if I miss a dose of Posaconazole?
If it's not too close to the time for your next dose, take the missed dose as soon as you remember. Do not double up on doses to compensate for a missed one.
Comprehensive Drug Guide
How Does Posaconazole Work?
Posaconazole is an antifungal medication that prevents the growth of fungi by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes.
What is Posaconazole Used For?
FDA Indications: Posaconazole is used to treat a certain type of fungal infection that can spread throughout the body (disseminated infections), severe fungal infections in patients who are intolerant to or are not responsive to other treatments, and preventing fungal infections in people with weak immune systems.
Common Dosages
Oral suspension: 40 mg/mL
Tablets: 100 mg
Delayedrelease tablets: 100 mg
Typical Dosing
FDA Approved Indications
- The dosing of Posaconazole depends on the type of infection being treated and the patient's health status. The typical dose ranges from 300 to 800 mg daily, divided into multiple doses.
Who Shouldn't Take Posaconazole?
- Have an allergy to it or other similar medications, such as Fluconazole or Itraconazole.
- Have a personal or family history of a certain heart problem (QT prolongation in the EKG).
- Have abnormal heartbeat rhythm (arrhythmia).
- Have liver disease.
- Are pregnant, planning to become pregnant, or breastfeeding.
Advice From The Pharmacist
- Take Posaconazole with a full meal for better absorption.
- Monitor the symptoms of your fungal infection and contact your healthcare provider if they are not improving or worsening.
- Report any new symptoms or adverse events to your healthcare provider.
Side Effects of Posaconazole
Common Side Effects
- diarrhea, nausea, headache, cough, fever, and low potassium levels in the blood.
Uncommon/Severe Side Effects
- liver damage or allergic reactions may occur.
Risks and Warnings of Posaconazole
- Posaconazole is not suitable for everyone. The risks associated with this medication need to be weighed against its benefits.
- The medication has been reported to cause serious heartrelated side effects in some individuals.
- Be aware that prolonged use of the drug can cause liver damage.
- The medication can interact with other drugs, which may potentiate its side effects or diminish its efficacy.
Interactions with Posaconazole
Common Drug Interactions
- certain antidepressants, antifungal medications, specific antibiotics, and certain heart medications.
Alternatives to Posaconazole
- Voriconazole
- Fluconazole
- Itraconazole
- Amphotericin B
- Caspofungin
