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Plenity
Plenity is a prescription medical device used for weight management in adults who are overweight or obese, with a Body Mass Index (BMI) of 25 to 40 kg/m². It is used in conjunction with diet and exercise to help individuals achieve weight loss. Plenity is composed of superabsorbent hydrogel particles, which, when taken before meals, absorb water in the stomach and create a feeling of fullness. This helps reduce overall food intake and supports gradual weight loss. Unlike medications, Plenity is classified as a medical device because it works mechanically rather than pharmacologically.
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Frequently Asked Questions
How long does it take for Plenity to start working?
Plenity begins working with the first dose by creating a feeling of fullness before meals. Weight loss results are typically seen over the course of several weeks to months when used in conjunction with diet and exercise.
Can I take Plenity if I have diabetes?
Yes, Plenity is safe for people with type 2 diabetes. However, it’s important to monitor your blood sugar levels closely and discuss any medication adjustments with your healthcare provider.
Is Plenity safe for long-term use?
Yes, Plenity is FDA-cleared for long-term use as part of a weight management plan that includes diet and exercise.
Does Plenity interact with medications?
Plenity is not absorbed into the bloodstream and has a low potential for interactions. However, you should space out the timing of Plenity and other oral medications by at least 30 minutes to avoid affecting the absorption of those medications.
Can I stop taking Plenity once I reach my goal weight?
Plenity is meant to be used as part of a long-term weight management strategy. Once you reach your goal weight, you should discuss ongoing maintenance with your healthcare provider to determine whether continuing Plenity is necessary.
Comprehensive Drug Guide
How Does Plenity Work?
Plenity works by utilizing superabsorbent hydrogel particles that expand in the stomach after being ingested with water. The hydrogel absorbs up to 100 times its weight in water, forming a gel-like mass that increases the volume in the stomach. This increased volume helps create a sense of fullness, leading to reduced food intake during meals. The hydrogel particles are not absorbed by the body and are naturally excreted through the digestive system.
Common Dosages
- 3 capsules taken twice daily with water, 20 to 30 minutes before lunch and dinner.
Typical Dosing
- Take 3 capsules with at least 16 oz (2 cups) of water approximately 20 to 30 minutes before lunch and dinner.
- Plenity should be used in conjunction with a reduced-calorie diet and regular physical activity.
- It is important to take Plenity as prescribed and drink the recommended amount of water to allow the hydrogel particles to work effectively.
Typical Dosing
FDA Approved Indications
- Weight management in adults with a Body Mass Index (BMI) between 25 and 40 kg/m² in conjunction with diet and exercise.
Who Shouldn't Take Plenity?
- Known hypersensitivity to any of the ingredients in Plenity.
- Pregnancy or breastfeeding, as the safety and efficacy of Plenity have not been established in these populations.
- Gastrointestinal disorders, such as severe gastroesophageal reflux disease (GERD) or difficulty swallowing, due to the potential for worsening symptoms.
Advice From The Pharmacist
- Take Plenity before meals with plenty of water (at least 16 oz) to ensure the capsules expand properly in the stomach and create a feeling of fullness.
- Drink additional water throughout the day to stay hydrated, as Plenity works by absorbing water.
- Plenity is designed to be used in combination with a healthy diet and regular physical activity for effective weight loss. It is not a standalone treatment for obesity or weight management.
- Swallow the capsules whole. Do not chew, crush, or open the capsules.
- Plenity is not absorbed into the bloodstream and is excreted naturally through the digestive system.
- If you experience difficulty swallowing the capsules or other gastrointestinal symptoms, contact your healthcare provider.
Side Effects of Plenity
Common Side Effects
- Bloating
- Abdominal pain or discomfort
- Diarrhea
- Flatulence
Uncommon/Severe Side Effects
- Gastrointestinal obstruction: Plenity can cause blockage in individuals with pre-existing conditions like narrowing of the esophagus or bowel.
- Difficulty swallowing: This may occur if not taken with sufficient water.
Risks and Warnings of Plenity
- Gastrointestinal Blockage: Individuals with a history of gastrointestinal issues, such as obstructions or severe motility disorders, should avoid using Plenity, as it may increase the risk of blockages.
- Dehydration: Since Plenity absorbs water, it’s important to stay adequately hydrated throughout the day to avoid dehydration.
- Choking or Difficulty Swallowing: Take Plenity with the recommended amount of water (16 oz) to avoid issues with swallowing or esophageal blockage.
Interactions with Plenity
Common Drug Interactions
- Medications for Gastrointestinal Issues: Use caution if you are taking medications for GI motility or have conditions affecting your digestive tract.
- Timing of Other Oral Medications: Because Plenity expands in the stomach, it may delay the absorption of other medications. Separate the timing of Plenity and other oral medications by at least 30 minutes.
Alternatives to Plenity
- Alli (orlistat): A weight loss medication that blocks the absorption of fat in the diet.
- Saxenda (liraglutide): A GLP-1 receptor agonist injection used for chronic weight management in patients with obesity.
- Contrave (naltrexone/bupropion): An oral medication that helps with weight loss by reducing hunger and food cravings.
- Phentermine: A prescription appetite suppressant used for short-term weight loss in combination with diet and exercise.
