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Phendimetrazine Tartrate ER
Phendimetrazine tartrate ER (extended-release) is a sympathomimetic amine used as a short-term adjunct in a weight management program. It is prescribed in conjunction with a reduced-calorie diet and exercise to assist in weight loss for obese individuals.
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Frequently Asked Questions
How quickly does phendimetrazine work?
Patients may begin to notice a decrease in appetite within hours of taking the medication.
Can I take phendimetrazine with food?
Yes, phendimetrazine can be taken with or without food. However, taking it with food may help to reduce gastrointestinal discomfort.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember in the morning. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Is phendimetrazine safe during pregnancy?
Phendimetrazine is not recommended during pregnancy. Consult your healthcare provider for alternatives.
What are the signs of serious side effects to watch for?
Monitor for signs of severe allergic reactions or significant changes in heart rate or blood pressure, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Phendimetrazine Tartrate ER Work?
Phendimetrazine works by stimulating the central nervous system (CNS), which increases heart rate and blood pressure, leading to a decrease in appetite. It enhances the release of norepinephrine in the brain, which plays a role in appetite control.
Common Dosages
- Extended-release capsules: Common strengths include 105 mg.
Typical Dosing
- Adults: The usual recommended dose is 1 capsule (105 mg) taken once daily, typically in the morning.
Typical Dosing
FDA Approved Indications
- Short-term management of obesity in conjunction with a weight management program that includes diet and exercise.
Who Shouldn't Take Phendimetrazine Tartrate ER?
- Known hypersensitivity to phendimetrazine or any component of the formulation.
- A history of cardiovascular disease, hyperthyroidism, or glaucoma.
- Current use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI.
Advice From The Pharmacist
- Take phendimetrazine exactly as prescribed, and do not exceed the recommended dose to avoid serious side effects.
- Avoid taking the medication late in the day to prevent insomnia.
- Maintain a balanced diet and exercise program for effective weight management.
Side Effects of Phendimetrazine Tartrate ER
Common Side Effects
- Dry mouth
- Insomnia
- Increased heart rate
- Nervousness or anxiety
Uncommon/Severe Side Effects
- Hypertension (high blood pressure)
- Cardiac arrhythmias
- Severe allergic reactions (rash, itching, swelling)
Risks and Warnings of Phendimetrazine Tartrate ER
- Cardiovascular Monitoring: Monitor heart rate and blood pressure regularly, especially in patients with pre-existing cardiovascular conditions.
- Dependence: Long-term use may lead to tolerance and dependence; regular follow-up with a healthcare provider is important.
Interactions with Phendimetrazine Tartrate ER
Common Drug Interactions
- Other Stimulants: Avoid combining with other stimulant medications, as this may increase the risk of side effects.
- MAOIs: Use caution with medications that may interact with phendimetrazine, including MAOIs.
Alternatives to Phendimetrazine Tartrate ER
- Other Weight Loss Medications: Such as orlistat or other appetite suppressants.
- Lifestyle Modifications: Diet and exercise programs that are effective in promoting weight loss.
