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Phendimetrazine Tartrate

Phendimetrazine tartrate is a stimulant medication used primarily as an appetite suppressant in the treatment of obesity. It is a member of the phenethylamine class and works by affecting the central nervous system to reduce hunger and increase energy expenditure. Phendimetrazine is typically prescribed as part of a comprehensive weight management program that includes diet and exercise.

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Frequently Asked Questions

How quickly can I expect to lose weight with Phendimetrazine?
Open FAQClose FAQ

Weight loss varies by individual, but many patients may begin to see results within the first few weeks when combined with a diet and exercise plan.

Can I take Phendimetrazine if I have high blood pressure?
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You should consult your healthcare provider, as phendimetrazine can increase blood pressure and may not be suitable for individuals with hypertension.

Is it safe to use Phendimetrazine for an extended period?
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Phendimetrazine is generally recommended for short-term use (a few weeks) as part of a broader weight loss strategy.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double up.

Can Phendimetrazine cause addiction?
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Yes, phendimetrazine has the potential for abuse and dependency. Use it only as prescribed, and communicate any concerns with your healthcare provider.

Comprehensive Drug Guide

How Does Phendimetrazine Tartrate Work?

Phendimetrazine works by stimulating the central nervous system, primarily affecting neurotransmitters such as norepinephrine and dopamine. This stimulation results in reduced appetite and increased energy levels, which can help patients adhere to dietary restrictions and improve weight loss outcomes.

Common Dosages

  • Tablets: 35 mg
  • Capsules: 105 mg

Typical Dosing

  • Adults: The usual dose is 35 mg taken 2-3 times a day before meals. The maximum recommended dose should not exceed 105 mg per day.
  • Pediatric use: Safety and effectiveness in children have not been established, and use is generally not recommended.


Typical Dosing

FDA Approved Indications

  • Short-term management of obesity in conjunction with a weight management program (diet and exercise).

Who Shouldn't Take Phendimetrazine Tartrate?

  • Known hypersensitivity to phendimetrazine or any component of the formulation
  • Severe hypertension or cardiovascular disease
  • Hyperthyroidism
  • Glaucoma
  • A history of drug abuse


Advice From The Pharmacist

  • Take Phendimetrazine as directed by your healthcare provider, typically before meals.
  • Avoid taking the medication late in the day to minimize the risk of insomnia.
  • Monitor your weight and follow a balanced diet and exercise program for best results.
  • Report any unusual side effects or concerns to your healthcare provider promptly.


Side Effects of Phendimetrazine Tartrate

Common Side Effects

  • Dry mouth
  • Insomnia
  • Dizziness
  • Increased heart rate


Uncommon/Severe Side Effects

  • Chest pain or palpitations
  • Severe anxiety or agitation
  • Signs of allergic reactions (rash, swelling, difficulty breathing)


Risks and Warnings of Phendimetrazine Tartrate

  • Cardiovascular Risk: Patients with existing heart conditions should be closely monitored, as stimulants can increase heart rate and blood pressure.
  • Dependence and Abuse: Due to its potential for abuse, patients should use this medication only as prescribed and for the intended duration.
  • Withdrawal Symptoms: Sudden discontinuation after prolonged use may lead to withdrawal symptoms such as fatigue and depression.


Interactions with Phendimetrazine Tartrate

Common Drug Interactions

  • Monoamine Oxidase Inhibitors (MAOIs): Use of phendimetrazine with MAOIs can lead to serious side effects, including hypertensive crises.
  • Other Stimulants: Combining phendimetrazine with other stimulant medications can increase the risk of cardiovascular side effects.

Common Food Interactions

  • Caffeine: Excessive caffeine intake can exacerbate side effects like jitteriness and insomnia.

Alternatives to Phendimetrazine Tartrate

  • Other Appetite Suppressants: Such as phentermine or lorcaserin.
  • Weight Management Programs: Behavioral therapy or lifestyle modification programs that emphasize diet and exercise.
  • Bariatric Surgery: For individuals with severe obesity when other methods have failed.