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Paxlovid (300/100)
Paxlovid is a novel oral antiviral drug developed by Pfizer and primarily used for treating COVID-19. The drug, composed of two key components, namely nirmatrelvir and ritonavir, is a roadblock that prevents the COVID-19 virus from multiplying inside your body. Therefore, your medical professional may prescribe Paxlovid if you're at a higher risk of developing severe illness.
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Frequently Asked Questions
Can I take Paxlovid if I have HIV?
Yes, Paxlovid can be taken by people with HIV. But, as always, talk to your healthcare provider to determine if it's the best choice for you.
Does Paxlovid interact with any other medications?
Yes, Paxlovid can interact with certain other medications, potentially influencing their effectiveness or causing negative side effects. Inform your doctor about all the medications you're currently taking, including any overthecounter medications, vitamins, and supplements.
How quickly does Paxlovid start working?
Paxlovid begins to work shortly after you take it, but its full effect may not be noticeable until after a few days of consistent use. Remember, it's vital you continue taking the medicine for the full course your doctor prescribes, even if you start feeling better.
Can I take Paxlovid with food?
According to the FDA guidelines, Paxlovid can be taken with or without food.
What should I do if I miss a dose of Paxlovid?
If you miss a dose of Paxlovid, take it as soon as you remember. However, if it's close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses.
Are there any side effects I should be concerned about with Paxlovid?
Like any medication, Paxlovid can cause side effects. Most are mild and go away independently, but some can be serious. Common side effects include diarrhea, nausea, and allergic reactions. Contact your healthcare provider immediately if you experience any severe or concerning side effects.
Can I have a glass of wine while on Paxlovid?
It's best to avoid alcohol while on this medication. Alcohol can exacerbate some side effects or interact with the medication. Speak with your healthcare provider for more personalized advice.
Comprehensive Drug Guide
How Does Paxlovid (300/100) Work?
Paxlovid, containing nirmatrelvir and ritonavir, is designed to inhibit the activity of the main protease, an essential enzyme for the reproduction of the SARSCoV2 virus, reducing severe symptoms and disease progression.
What is Paxlovid (300/100) Used For?
Paxlovid is used to treat mild to moderate COVID-19 in adults and pediatric patients (12 years of age and older, weighing at least 40 kg) who have a positive result of direct SARSCoV2 viral testing and who are at high risk for progression to severe COVID-19.
Common Dosages
Paxlovid is commonly manufactured in the tablet formulation of Nirmatrelvir 150 mg/Ritonavir 100 mg.
Typical Dosing
FDA Approved Indications
One nirmatrelvir 150 mg/ritonavir 100 mg tablet taken with food orally every 12 hours for five days.
Who Shouldn't Take Paxlovid (300/100)?
- People who have severe liver or kidney disease.
- Pregnant women or breastfeeding mothers (as safe use not fully studied).
Advice From The Pharmacist
- Paxlovid should be taken with food for optimal absorption.
- It's critical to complete the full course of therapy, even if symptoms improve.
- Interactions with certain other medications can occur. It's important to keep your healthcare provider informed of all the drugs you're taking.
Side Effects of Paxlovid (300/100)
Common Side Effects
- Altered taste
- Diarrhea
- Nausea
Uncommon/Severe Side Effects
If you experience severe allergic reactions, immediately contact your healthcare provider.
Interactions with Paxlovid (300/100)
Common Drug Interactions
Certain cholesterol medicines:
- Atorvastatin
- Lovastatin
- Simvastatin
Certain heart medications:
- Amiodarone
- Digoxin
- Dronedarone
- Quinidine
- Verapamil
Certain antipsychotic drugs:
- Pimozide
- Lurasidone
- Quetiapine
Certain seizure medications:
- Carbamazepine
- Clonazepam
- Phenytoin
- Phenobarbital
Certain HIV medications:
- Other protease inhibitors, such as ritonavir, can affect their levels.
- The combination of efavirenz, emtricitabine, and tenofovir.
Alternatives to Paxlovid (300/100)
- Remdesivir (Veklury)
- Molnupiravir (Lagevrio)
