You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Pamelor
Pamelor, the brand name for nortriptyline, is a tricyclic antidepressant (TCA) used to treat depression and, at times, other conditions such as chronic pain or anxiety disorders. It works by affecting certain neurotransmitters in the brain, primarily norepinephrine and serotonin, which help regulate mood and emotional balance. Pamelor is sometimes prescribed off-label for conditions like nerve pain (neuropathy) and migraine prevention.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Pamelor ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Pamelor to work?
It may take 2 to 4 weeks to notice an improvement in symptoms of depression. For chronic pain or migraines, symptom relief may be noticed sooner, but full effects can take several weeks.
Can Pamelor be used for pain?
Yes, Pamelor is often used off-label for the treatment of nerve pain (neuropathy) and migraine prevention. It helps by modifying how pain signals are processed by the brain.
What should I do if I miss a dose of Pamelor?
If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses.
Is Pamelor safe for long-term use?
Yes, Pamelor is commonly used for long-term treatment of depression and other conditions. However, regular monitoring by your healthcare provider is recommended to ensure continued safety and effectiveness.
Can Pamelor cause weight gain?
Weight gain can be a side effect of Pamelor, especially with long-term use. Maintaining a balanced diet and regular physical activity can help manage this side effect.
Comprehensive Drug Guide
How Does Pamelor Work?
Pamelor (nortriptyline) works by increasing the levels of the neurotransmitters norepinephrine and serotonin in the brain by inhibiting their reuptake into nerve cells. This helps to improve mood, reduce feelings of anxiety, and alleviate symptoms of depression. The drug also has some anticholinergic effects, which can contribute to its side effects profile.
Common Dosages
- Capsules: 10 mg, 25 mg, 50 mg, 75 mg
- Oral solution: 10 mg/5 mL
Typical Dosing
- For depression: The typical starting dose is 25 mg once daily, which may be taken in divided doses. The dose may be adjusted by the healthcare provider based on response, with a usual range of 25 to 150 mg per day.
- For chronic pain or migraine prevention: The dose may be lower, typically starting at 10-25 mg daily, and gradually increasing if necessary.
Typical Dosing
FDA Approved Indications
- Treatment of depression.
It may also be used off-label for:
- Neuropathic pain (nerve pain)
- Migraine prevention
- Anxiety disorders
Who Shouldn't Take Pamelor?
- Recent heart attack (myocardial infarction).
- Known hypersensitivity to nortriptyline or other tricyclic antidepressants.
- Concurrent use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI.
- Severe liver disease.
Advice From The Pharmacist
- Take Pamelor as prescribed, usually once daily or in divided doses. It can be taken with or without food. If it causes drowsiness, it may be better to take it at night.
- Avoid alcohol while taking Pamelor, as it can increase the risk of side effects like drowsiness or dizziness.
- Do not stop taking Pamelor suddenly without consulting your healthcare provider, as doing so can cause withdrawal symptoms or worsen your condition. Your dose should be tapered gradually.
- Monitor your mood: If you experience worsening depression, suicidal thoughts, or significant mood changes, contact your healthcare provider immediately.
- Stay hydrated: Since Pamelor can have anticholinergic effects, it may cause dry mouth, constipation, and other symptoms related to reduced secretions.
Side Effects of Pamelor
Common Side Effects
- Dry mouth
- Constipation
- Drowsiness or dizziness
- Blurred vision
- Weight gain
- Increased heart rate
Uncommon/Severe Side Effects
- Suicidal thoughts or behaviors: Particularly in young adults or children.
- Heart rhythm problems (arrhythmias): This may occur, especially in individuals with pre-existing heart conditions.
- Seizures: Though rare, tricyclic antidepressants can lower the seizure threshold.
Risks and Warnings of Pamelor
- Risk of suicide: Antidepressants, including Pamelor, may increase the risk of suicidal thoughts and behavior in adolescents and young adults. Regular monitoring by healthcare providers is recommended during the start of treatment or when adjusting doses.
- Cardiovascular risk: Pamelor can cause heart rhythm disturbances, particularly in individuals with pre-existing heart conditions. Monitoring for symptoms like palpitations, shortness of breath, or chest pain is advised.
- Anticholinergic effects: Pamelor can cause dry mouth, blurred vision, urinary retention, and constipation. These effects may be more pronounced in older adults.
Interactions with Pamelor
Common Drug Interactions
- Monoamine oxidase inhibitors (MAOIs): Do not use Pamelor with MAOIs, as it can lead to serious and potentially life-threatening interactions.
- Blood pressure medications: Pamelor can increase blood pressure in some individuals, so careful monitoring may be necessary.
- CNS depressants: Pamelor can increase the sedative effects of other central nervous system depressants such as alcohol, benzodiazepines, or opioids.
- Anticholinergic drugs: Medications with anticholinergic properties (e.g., antihistamines, tricyclic antidepressants) can increase the risk of side effects like dry mouth, blurred vision, and constipation when used with Pamelor.
Alternatives to Pamelor
- Amitriptyline (Elavil): Another tricyclic antidepressant used to treat depression, chronic pain, and migraines.
- Sertraline (Zoloft): A selective serotonin reuptake inhibitor (SSRI) often used to treat depression, anxiety disorders, and other mood disorders.
- Venlafaxine (Effexor): A serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat depression and anxiety.
