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Orphenadrine Citrate

Orphenadrine is primarily employed as a muscle relaxer to relieve pain and discomfort caused by strains, sprains, and other muscle injuries. It also has anticholinergic properties, making it useful in certain medical situations.

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Frequently Asked Questions

Is Orphenadrine a painkiller?
Open FAQClose FAQ

No, Orphenadrine is a muscle relaxant. It's used to relieve muscle pain and stiffness caused by strains, sprains, or other injuries. It's not used for general pain relief.

Does Orphenadrine make you drowsy?
Open FAQClose FAQ

Yes, drowsiness is a common side effect of Orphenadrine. Avoid driving or operating machinery until you know how Orphenadrine affects you.

Can I just stop Orphenadrine after my symptoms are gone?
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No, it's not recommended. Stopping Orphenadrine suddenly can cause withdrawal symptoms. Your doctor will likely taper your dosage before stopping the medication.

Does Orphenadrine interact with other medications?
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Yes, Orphenadrine can interact with various other medications, ranging from antidepressants to antihistamines, and more. Always inform your doctor about all other medications you're taking before starting Orphenadrine.

Comprehensive Drug Guide

How Does Orphenadrine Citrate Work?

Prednisone is a centrally-acting muscle relaxant with anticholinergic properties that help to alleviate painful muscle spasms.

What is Orphenadrine Citrate Used For?

FDA indications: Orphenadrine is primarily used to help ease particular muscular conditions such as strains, sprains, and other muscle injuries.

Off-label uses: Due to its anticholinergic properties, it provides symptomatic relief in conditions where anticholinergic influence is desired.

Common Dosages

Extended-Release Tablets: 100mg

Typical Dosing

FDA Approved Indications

  • For FDA-approved indications: For muscular injuries and spasms, the commonly suggested dose is 100mg orally twice a day.

Off-Label Uses

  • For off-label uses: dosage depends on the condition the drug is being used to treat.

Who Shouldn't Take Orphenadrine Citrate?

  • Have allergies to Orphenadrine or any of its components.
  • Have Glaucoma (raised pressure in your eye).
  • Have issues with urinary tract or bladder obstruction.
  • Suffer from a form of muscle weakness called myasthenia gravis.
  • Have intestinal problems like esophageal obstruction, achalasia, and paralytic ileus.
  • Are breastfeeding, it's not known whether orphenadrine harms the baby.

Advice From The Pharmacist

  • Stay hydrated. Orphenadrine may cause dry mouth and staying hydrated can help.
  • This medication can make you dizzy or drowsy. So, avoid undertaking activities that require alertness until you?re sure of how Orphenadrine affects you.
  • Don't halt the medication without your doctor's advice. A sudden discontinuation might trigger withdrawal symptoms.
  • If you're feeling unusually agitated, restless, or are facing insomnia, notify your doctor right away. These could be signs of an overdose.

Side Effects of Orphenadrine Citrate

Common Side Effects

  • Common side effects:
  • You might feel dizzy, drowsy, dry mouth, and blurred vision.
  • Severe side effects:
  • If you feel severely restless, face a lack of coordination, or have a rapid heartbeat, or high temperature, seek medical help immediately.

Risks and Warnings of Orphenadrine Citrate

  • Orphenadrine promises relief from muscle spasms, but it's not for all. For instance, if you're allergic to it, step away. Also, individuals with glaucoma, enlarged prostate, blockages in the stomach/intestines, and myasthenia gravis should proceed with caution or avoid usage entirely.
  • Patients with heart diseases should be aware. Orphenadrine is known to cause rapid or irregular heartbeats. If you have a history of heart conditions, consult your doctor before starting the medication.
  • Are you dealing with high blood pressure issues? If yes, tread lightly. Orphenadrine may potentially raise your blood pressure and hence should be taken under medical supervision.
  • Pregnant or breastfeeding? Your baby's safety is paramount. The effects of Orphenadrine on the unborn and newborn are still under exploration. Discuss with your healthcare provider then proceed with utmost caution.
  • Individuals with liver or kidney diseases should be extra cautious. Orphenadrine, being metabolized in the liver and excreted by the kidneys, can stress those vital organs if they're already weakened.
  • Mental health and sleep disorder patients, take special care. Orphenadrine can worsen certain psychological conditions and sleep disturbances. Check-in with your healthcare provider for guidance.
  • Lastly, Orphenadrine can cause dry mouth and impair your vision temporarily, which may interfere with activities such as driving. Exercise caution and refrain from high-risk tasks when on this medication.

Interactions with Orphenadrine Citrate

Common Drug Interactions

  • Antihistamines (like diphenhydramine, loratadine)
  • Antipsychotics
  • Benzodiazepines
  • Antidepressants
  • Alcohol

Alternatives to Orphenadrine Citrate

  • Methocarbamol
  • Cyclobenzaprine
  • Carisoprodol
  • Metaxalone
  • Tizanidine