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Nuvigil

Nuvigil (armodafinil) is a stimulant medication used to improve wakefulness in adults with excessive sleepiness due to conditions such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It helps promote alertness and reduce fatigue.



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Frequently Asked Questions

How quickly does Nuvigil work?
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Nuvigil typically starts to promote wakefulness within 1 to 2 hours after taking it.

Can I take Nuvigil with food?
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Nuvigil can be taken with or without food; however, taking it consistently the same way may help with adherence.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.

Is Nuvigil safe during pregnancy?
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Nuvigil should be used during pregnancy only if the potential benefits justify the potential risks. Consult your healthcare provider for guidance.

What are the signs of serious side effects to watch for?
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Monitor for signs of severe allergic reactions or psychiatric symptoms, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does Nuvigil Work?

Armodafinil's exact mechanism of action is not fully understood, but it is believed to work by increasing the levels of certain neurotransmitters in the brain, such as dopamine, which promotes wakefulness and alertness.

Common Dosages

  • Tablets: Common strengths include 150 mg and 250 mg.

Typical Dosing

  • Adults: The usual recommended dose is 150 mg taken orally once daily in the morning for narcolepsy and obstructive sleep apnea, or about 1 hour prior to the start of the work shift for shift work sleep disorder.


Typical Dosing

FDA Approved Indications

  • Treatment of excessive sleepiness associated with narcolepsy.
  • Treatment of excessive sleepiness associated with obstructive sleep apnea.
  • Improvement of wakefulness in individuals with shift work sleep disorder.

Who Shouldn't Take Nuvigil?

  • Known hypersensitivity to armodafinil or any component of the formulation.
  • A history of severe rash or hypersensitivity reactions related to modafinil or armodafinil.


Advice From The Pharmacist

  • Take Nuvigil exactly as prescribed, and do not exceed the recommended dose.
  • Be aware that Nuvigil may cause side effects such as headache, dizziness, or insomnia; report any persistent issues to your healthcare provider.
  • Avoid alcohol and other CNS depressants while taking Nuvigil, as these can enhance side effects.


Side Effects of Nuvigil

Common Side Effects

  • Headache
  • Nausea
  • Dizziness
  • Insomnia
  • Dry mouth


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Psychiatric symptoms (anxiety, hallucinations, aggression)
  • Serious skin reactions (Stevens-Johnson syndrome)


Risks and Warnings of Nuvigil

  • Psychiatric Effects: Monitor for changes in mood or behavior, especially in individuals with a history of mental health issues.
  • Dependency: Although the risk is low, there is potential for abuse; regular follow-up with a healthcare provider is important.

Interactions with Nuvigil

Common Drug Interactions

  • CNS Depressants: Use caution when combining with other medications that affect the CNS, as this can increase side effects.
  • Anticoagulants and Hormonal Contraceptives: Inform your healthcare provider about all medications you are taking, as armodafinil may affect the metabolism of these drugs.

Alternatives to Nuvigil

  • Other Stimulants: Such as modafinil for similar indications.
  • Non-stimulant Medications: Such as sodium oxybate for narcolepsy.