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Nurtec
Nurtec ODT (rimegepant) is a medication used for the acute treatment of migraine and for the prevention of episodic migraine. It is part of a class of drugs known as CGRP (calcitonin gene-related peptide) receptor antagonists, which work by blocking the action of CGRP, a molecule involved in migraine attacks.
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Frequently Asked Questions
How quickly does Nurtec ODT work?
Most patients begin to experience relief within 1 to 2 hours after taking the medication.
Can I take Nurtec ODT with food?
Yes, Nurtec ODT can be taken with or without food.
What should I do if I miss a dose?
Nurtec ODT is intended for use as needed for migraines, so there is no scheduled dosing. If you forget to take it during a migraine, take it as soon as you remember.
Are there any dietary restrictions while using Nurtec ODT?
There are no specific dietary restrictions while using Nurtec ODT.
Is Nurtec ODT safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Nurtec ODT during these periods.
Comprehensive Drug Guide
How Does Nurtec Work?
Nurtec ODT works by blocking the CGRP receptor, preventing the action of CGRP, which is released during a migraine attack. By inhibiting this pathway, Nurtec helps to reduce the frequency and severity of migraine episodes.
Common Dosages
- Orally Disintegrating Tablets: Each tablet contains 75 mg of rimegepant.
Typical Dosing
- For acute treatment: The recommended dose is 75 mg taken orally as needed for migraine attacks. A second dose may be taken if the migraine returns after 2 hours, but do not exceed 75 mg in 24 hours.
Typical Dosing
FDA Approved Indications
- Acute Treatment of Migraine: for the treatment of migraine attacks in adults.
- Preventive Treatment of Episodic Migraine: to reduce the frequency of migraine attacks.
Who Shouldn't Take Nurtec?
- Known hypersensitivity to rimegepant or any component of the formulation.
Advice From The Pharmacist
- Take Nurtec ODT as soon as you feel a migraine coming on for optimal effectiveness.
- The tablet can be taken without water and dissolves in the mouth.
- Keep track of the frequency of migraines to discuss with your healthcare provider for potential preventive therapy.
Side Effects of Nurtec
Common Side Effects
- Nausea
- Vomiting
- Dry mouth
- Fatigue
- Dizziness
Uncommon/Severe Side Effects
- Allergic reactions (rash, itching, swelling)
- Signs of liver problems (elevated liver enzymes).
Risks and Warnings of Nurtec
- Medication Overuse: Avoid overuse of migraine medications, as this can lead to rebound headaches.
- Liver Function: Monitor liver function, especially in patients with pre-existing liver disease.
Interactions with Nurtec
Common Drug Interactions
- CYP3A4 Inhibitors and Inducers: Rimegepant is primarily metabolized by CYP3A4, so drugs that affect this enzyme may alter its efficacy and safety.
Alternatives to Nurtec
- Other CGRP Antagonists: Such as ubrogepant for similar indications.
- Triptans: Like sumatriptan or rizatriptan for acute migraine treatment.
