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Nuju
Nuju (naltrexone/bupropion) is a combination medication used for the management of chronic weight management in adults who are overweight or obese. It is typically prescribed as part of a comprehensive weight loss program that includes diet and exercise.
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Frequently Asked Questions
How quickly does Nuju work?
Patients may begin to notice weight loss results within a few weeks, but optimal effects may take longer and vary by individual.
Can I take Nuju with food?
Nuju can be taken with or without food; however, taking it with food may help reduce gastrointestinal side effects.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Is Nuju safe during pregnancy?
Nuju is not recommended during pregnancy. Consult your healthcare provider for alternatives if you are pregnant or planning to become pregnant.
What are the signs of serious side effects to watch for?
Monitor for signs of severe allergic reactions, seizures, or significant mood changes, and seek immediate medical attention if these occur.
Comprehensive Drug Guide
How Does Nuju Work?
Nuju combines the effects of naltrexone and bupropion. Naltrexone is an opioid receptor antagonist that may help reduce cravings, while bupropion is an antidepressant that can help with mood and energy levels. Together, they help to regulate appetite and support weight loss.
What is Nuju Used For?
Common Dosages
- Extended-release tablets: Usually available in a combination of 8 mg naltrexone and 90 mg bupropion.
Typical Dosing
- Adults: The usual recommended dose is one tablet taken orally once daily in the morning, gradually increasing based on tolerance and effectiveness.
Typical Dosing
FDA Approved Indications
- Chronic weight management in adults as an adjunct to a reduced-calorie diet and increased physical activity.
Who Shouldn't Take Nuju?
- Known hypersensitivity to naltrexone, bupropion, or any component of the formulation.
- Seizure disorders, eating disorders, or concurrent use of monoamine oxidase inhibitors (MAOIs).
Advice From The Pharmacist
- Take Nuju exactly as prescribed, and do not exceed the recommended dose.
- Monitor for any changes in mood or behavior, especially during the initial treatment period.
- Discuss any history of substance abuse with your healthcare provider, as naltrexone may precipitate withdrawal in opioid-dependent individuals.
Side Effects of Nuju
Common Side Effects
- Nausea
- Headache
- Dizziness
- Insomnia
- Dry mouth
Uncommon/Severe Side Effects
- Seizures
- Severe allergic reactions (rash, itching, swelling)
- Liver problems (symptoms may include jaundice or dark urine)
Risks and Warnings of Nuju
- Seizure Risk: There is a risk of seizures, particularly in individuals with a history of seizure disorders. Careful monitoring is essential.
- Liver Function: Liver function should be monitored, especially in patients with pre-existing liver disease.
Interactions with Nuju
Common Drug Interactions
Other Medications: Inform your healthcare provider about all medications you are taking, particularly those affecting the central nervous system or metabolic pathways.
Alternatives to Nuju
- Other Weight Management Medications: Such as phentermine/topiramate or orlistat for similar indications.
- Lifestyle Modifications: Diet and exercise programs can also support weight loss efforts without medication.
