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Neuraptine
Neuraptine (generic name: gabapentin) is a medication primarily used to manage neuropathic pain and as an adjunct therapy for the treatment of seizures in adults and children. It is also commonly prescribed for conditions such as restless legs syndrome and fibromyalgia.
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Frequently Asked Questions
How quickly does Neuraptine work?
Patients may start to notice improvements in pain or seizure control within 1 to 2 weeks, but it may take longer for optimal effects.
Can I take Neuraptine with food?
Yes, Neuraptine can be taken with or without food.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using Neuraptine?
There are no specific dietary restrictions while using Neuraptine, but a balanced diet is recommended for overall health.
Is Neuraptine safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Neuraptine, as its safety during these periods is not fully established.
Comprehensive Drug Guide
How Does Neuraptine Work?
Gabapentin works by modulating the release of excitatory neurotransmitters, inhibiting the activity of certain calcium channels in the central nervous system. This action reduces the abnormal electrical activity that causes seizures and helps alleviate neuropathic pain by calming overactive nerves.
Common Dosages
- Capsules: 100 mg, 300 mg, and 400 mg.
- Tablets: 600 mg and 800 mg.
- Oral Solution: 250 mg/5 mL.
Typical Dosing
- For neuropathic pain: The usual starting dose for adults is 300 mg taken orally at bedtime, which can be gradually increased up to 600 mg to 900 mg per day divided into two or three doses.
- For seizures: The starting dose is often 300 mg taken orally on the first day, followed by increased dosing based on individual response.
Typical Dosing
FDA Approved Indications
- Neuropathic Pain: associated with diabetic neuropathy and postherpetic neuralgia.
- Seizures: as adjunctive therapy for partial seizures in adults and children over 3 years of age.
Who Shouldn't Take Neuraptine?
- Known hypersensitivity to gabapentin or any component of the formulation.
Advice From The Pharmacist
- Take Neuraptine exactly as prescribed, and do not abruptly discontinue the medication without consulting your healthcare provider, as this may increase seizure risk.
- Monitor for side effects such as dizziness, drowsiness, and fatigue, especially when starting treatment or increasing the dose.
- Avoid alcohol and other CNS depressants, as they may enhance the sedative effects of gabapentin.
Side Effects of Neuraptine
Common Side Effects
- Dizziness
- Drowsiness
- Fatigue
- Nausea
- Peripheral edema (swelling of limbs)
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Mood changes (depression, anxiety)
- Suicidal thoughts or behavior.
Risks and Warnings of Neuraptine
- Suicidal Thoughts: Gabapentin has been associated with an increased risk of suicidal thoughts and behaviors; patients should be monitored for changes in mood or behavior.
- CNS Effects: Caution is advised in patients with a history of substance use disorder due to the potential for abuse.
Interactions with Neuraptine
Common Drug Interactions
- CNS Depressants: Use caution when combining with other medications that cause sedation (e.g., opioids, benzodiazepines).
- Antacids: Certain antacids may decrease the absorption of gabapentin; it is advisable to space doses appropriately.
Alternatives to Neuraptine
- Other Anticonvulsants: Such as pregabalin or lamotrigine for similar indications.
- Pain Management: Other medications like NSAIDs or tricyclic antidepressants may also be considered for neuropathic pain.
