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Naftin

Naftin (generic name: naftifine) is a topical antifungal medication used primarily to treat tinea infections, including athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It works by inhibiting the growth of fungi, helping to alleviate symptoms and clear infections.



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Frequently Asked Questions

How quickly does Naftin work?
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Many patients notice improvement in their condition within a few days of starting treatment, but it is important to complete the full course to ensure the infection is fully cleared.

Can I use Naftin with other skin products?
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Yes, but it’s best to apply Naftin first and allow it to dry before applying other topical products.

What should I do if I miss a dose?
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If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next application, skip the missed dose and continue with your regular schedule.

Are there any dietary restrictions while using Naftin?
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There are no specific dietary restrictions while using Naftin.

Is Naftin safe during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Naftin.

Comprehensive Drug Guide

How Does Naftin Work?

Naftifine works by inhibiting the enzyme squalene epoxidase, which is essential for the biosynthesis of ergosterol, an important component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately the death of the fungal cells.



Common Dosages

  • Topical Cream: 1% formulation.
  • Topical Gel: 1% formulation.

Typical Dosing

  • Apply a thin layer of Naftin cream or gel to the affected area once daily for 2 to 4 weeks, depending on the severity of the infection.


Typical Dosing

FDA Approved Indications

  • Tinea Pedis: for the treatment of athlete's foot.
  • Tinea Cruris: for the treatment of jock itch.
  • Tinea Corporis: for the treatment of ringworm.


Who Shouldn't Take Naftin?

  • Known hypersensitivity to naftifine or any component of the formulation.
  • Open wounds or on mucous membranes unless directed by a healthcare provider.


Advice From The Pharmacist

  • Apply Naftin to clean, dry skin and avoid contact with eyes and mucous membranes.
  • Wash hands before and after application to prevent the spread of infection.
  • Continue using the medication for the full prescribed duration, even if symptoms improve, to ensure the infection is fully cleared.


Side Effects of Naftin

Common Side Effects

  • Skin irritation
  • Burning or stinging sensation at the application site
  • Itching or rash
  • Dryness of the skin


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Signs of a secondary infection.


Risks and Warnings of Naftin

  • Local Irritation: Monitor for signs of local irritation or worsening skin condition; discontinue use if severe reactions occur.
  • Not for Systemic Use: Naftin is for topical use only and should not be applied to open wounds or mucous membranes.


Interactions with Naftin

Common Drug Interactions

  • Other Topical Agents: Use caution when applying naftifine with other topical medications to avoid irritation.


Common Food Interactions


Alternatives to Naftin

  • Other Topical Antifungals: Such as clotrimazole or terbinafine for similar indications.
  • Oral Antifungals: For more extensive or severe fungal infections.