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Metoprolol Tartrate
Metoprolol tartrate is a beta-adrenergic blocker commonly used to treat conditions such as hypertension (high blood pressure), angina (chest pain), and to improve survival after a heart attack. It works by blocking the effects of adrenaline on beta receptors, which reduces heart rate and blood pressure.
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Frequently Asked Questions
How quickly does metoprolol tartrate work?
Patients may begin to notice effects on blood pressure within a few hours, with optimal control typically established after several days.
Can I take metoprolol tartrate with food?
Yes, it can be taken with or without food; however, consistency in how you take it is important.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using metoprolol tartrate?
There are no specific dietary restrictions, but a balanced diet is advisable to help manage overall health.
Is metoprolol tartrate safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using metoprolol.
Comprehensive Drug Guide
How Does Metoprolol Tartrate Work?
Metoprolol selectively blocks beta-1 adrenergic receptors in the heart, leading to a decrease in heart rate and myocardial contractility. This action helps to lower blood pressure and reduce the heart's workload.
Common Dosages
- Tablets: 25 mg, 50 mg, and 100 mg.
- Injectable Solution: 5 mg/mL.
Typical Dosing
- For hypertension, the usual starting dose is 50 mg taken orally once or twice daily, with adjustments based on individual response. The maximum recommended daily dose can be up to 400 mg.
- For angina, dosing may start at 50 mg twice daily, with adjustments as needed.
Typical Dosing
FDA Approved Indications
- Hypertension: to lower blood pressure.
- Angina: for the management of chest pain.
- Myocardial Infarction: to improve survival following a heart attack.
Who Shouldn't Take Metoprolol Tartrate?
- Known hypersensitivity to metoprolol or any component of the formulation.
- Severe bradycardia (slow heart rate).
- Advanced atrioventricular block (unless a pacemaker is present).
- Decompensated heart failure or cardiogenic shock.
Advice From The Pharmacist
- Take metoprolol exactly as prescribed, and do not stop taking it suddenly without consulting your healthcare provider, as this may lead to worsening symptoms.
- Monitor blood pressure and heart rate regularly while on this medication.
- Avoid alcohol and certain over-the-counter medications that may affect blood pressure.
Side Effects of Metoprolol Tartrate
Common Side Effects
- Fatigue
- Dizziness
- Depression
- Cold extremities
- Slow heart rate
Uncommon/Severe Side Effects
- Severe hypotension (low blood pressure)
- Heart block
- Respiratory issues (in asthmatic patients)
Risks and Warnings of Metoprolol Tartrate
- Bradycardia: Monitor heart rate; dosage adjustments may be necessary if bradycardia occurs.
- Withdrawal Symptoms: Abrupt discontinuation can lead to rebound hypertension or angina; tapering is recommended.
- Respiratory Effects: Use with caution in patients with asthma or other respiratory conditions.
Interactions with Metoprolol Tartrate
Common Drug Interactions
- CNS Depressants: Use caution when combining with other CNS depressants, as they may increase sedation.
- Other Antihypertensives: Monitor blood pressure closely if used in combination with other antihypertensive agents.
Alternatives to Metoprolol Tartrate
- Other Beta-Blockers: Such as atenolol or carvedilol for similar indications.
- Calcium Channel Blockers: Such as amlodipine or diltiazem for hypertension and angina management.
