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Methamphetamine HCl

Methamphetamine HCl is a powerful central nervous system stimulant that is primarily used in a medical context for the treatment of attention deficit hyperactivity disorder (ADHD) and certain cases of obesity. However, it is more commonly known for its illegal use as a recreational drug.



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Frequently Asked Questions

How quickly does Methamphetamine HCl work?
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Patients may begin to notice improvements in symptoms of ADHD within 1 to 2 hours after taking the medication.

Can I take Methamphetamine HCl with food?
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Yes, it can be taken with or without food; however, taking it consistently the same way may help with adherence.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.

Is Methamphetamine HCl safe during pregnancy?
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Methamphetamine should be used during pregnancy only if the potential benefits justify the potential risks. Consult your healthcare provider for guidance.

What are the signs of serious side effects to watch for?
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Monitor for signs of severe allergic reactions, significant mood changes, and cardiovascular symptoms, and seek immediate medical attention if these occur.

Comprehensive Drug Guide

How Does Methamphetamine HCl Work?

Methamphetamine increases the release of neurotransmitters such as dopamine and norepinephrine in the brain, leading to increased alertness, energy, and euphoria. This action also reduces appetite and can enhance focus and attention in individuals with ADHD.

Common Dosages

  • Tablets: Common strengths include 5 mg and 10 mg.

Typical Dosing

  • For ADHD: The usual starting dose is 5 mg once or twice daily, with potential adjustments based on clinical response.
  • For Obesity: Dosing may start at 5 mg once daily, taken before breakfast or 1-2 hours after breakfast, with the possibility of increasing as needed.


Typical Dosing

FDA Approved Indications

  • Treatment of attention deficit hyperactivity disorder (ADHD) in patients aged 6 years and older.
  • Short-term management of obesity in conjunction with a comprehensive treatment plan including diet and exercise.

Who Shouldn't Take Methamphetamine HCl?

  • Known hypersensitivity to methamphetamine or any component of the formulation.
  • Severe anxiety, agitation, or tension.
  • A history of substance abuse or dependence.


Advice From The Pharmacist

  • Take Methamphetamine HCl exactly as prescribed and do not exceed the recommended dosage.
  • Monitor for any changes in mood or behavior, particularly in children and adolescents.
  • Avoid alcohol and other CNS depressants while taking methamphetamine, as these can enhance side effects.


Side Effects of Methamphetamine HCl

Common Side Effects

  • Insomnia
  • Decreased appetite
  • Weight loss
  • Increased heart rate
  • Nervousness or anxiety


Uncommon/Severe Side Effects

  • Cardiovascular events (e.g., elevated blood pressure, heart attack)
  • Severe allergic reactions (rash, itching, swelling)
  • Psychiatric symptoms (aggression, hallucinations)


Risks and Warnings of Methamphetamine HCl

  • Addiction and Abuse: Methamphetamine has a high potential for addiction; careful monitoring and regular follow-up with a healthcare provider are essential.
  • Withdrawal Symptoms: Abrupt discontinuation after long-term use can lead to withdrawal symptoms.


Interactions with Methamphetamine HCl

Common Drug Interactions

  • CNS Depressants: Use caution when combining with other CNS depressants, as this can increase the risk of respiratory depression and sedation.
  • Other Stimulants: Inform your healthcare provider about all medications you are taking to avoid potential interactions.


Alternatives to Methamphetamine HCl

  • Other Stimulants: Such as amphetamine/dextroamphetamine for similar indications in ADHD treatment.
  • Non-stimulant Medications: Such as atomoxetine (Strattera) for managing ADHD.