You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Lyllana
Lyllana is a transdermal hormone replacement therapy (HRT) patch containing estradiol, a synthetic form of the hormone estrogen. It is primarily used to treat symptoms of menopause, such as hot flashes, night sweats, vaginal dryness, and osteoporosis prevention in postmenopausal women. By replacing the estrogen that the body no longer produces naturally after menopause, Lyllana helps manage symptoms and reduces the risk of osteoporosis. It is often prescribed to women who have undergone hysterectomy, but if the uterus is still intact, Lyllana is usually given with a progestin to reduce the risk of uterine cancer.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Lyllana ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How soon will I feel relief from menopausal symptoms after starting Lyllana?
Relief from hot flashes and other menopausal symptoms may begin within a few weeks, but full effects may take up to several months.
How soon will I feel relief from menopausal symptoms after starting Lyllana?
Relief from hot flashes and other menopausal symptoms may begin within a few weeks, but full effects may take up to several months.
Can Lyllana be used to prevent osteoporosis?
Yes, Lyllana is approved for the prevention of postmenopausal osteoporosis, but it is typically prescribed to women who cannot take other medications for osteoporosis.
Can Lyllana be used to prevent osteoporosis?
Yes, Lyllana is approved for the prevention of postmenopausal osteoporosis, but it is typically prescribed to women who cannot take other medications for osteoporosis.
Can Lyllana be used to prevent osteoporosis?
Yes, Lyllana is approved for the prevention of postmenopausal osteoporosis, but it is typically prescribed to women who cannot take other medications for osteoporosis.
Can Lyllana be used to prevent osteoporosis?
Yes, Lyllana is approved for the prevention of postmenopausal osteoporosis, but it is typically prescribed to women who cannot take other medications for osteoporosis.
Can Lyllana be used to prevent osteoporosis?
Yes, Lyllana is approved for the prevention of postmenopausal osteoporosis, but it is typically prescribed to women who cannot take other medications for osteoporosis.
What should I do if my patch falls off?
If the patch falls off, try to reapply it to a clean, dry area. If it does not stick, replace it with a new patch and continue your regular schedule.
Can Lyllana cause weight gain?
Weight changes, including weight gain, are possible side effects of Lyllana, but they are not common. If you experience significant weight changes, consult your healthcare provider.
Can Lyllana be used by women who still have a uterus?
Yes, but women with an intact uterus should take a progestin in addition to Lyllana to reduce the risk of endometrial cancer.
Comprehensive Drug Guide
How Does Lyllana Work?
Lyllana works by supplying estradiol, which is a form of estrogen, through the skin and into the bloodstream. Estradiol helps alleviate menopausal symptoms by replacing the estrogen that the ovaries no longer produce after menopause. Estrogen plays a crucial role in regulating body temperature, maintaining vaginal health, and preserving bone density. By restoring estrogen levels, Lyllana helps reduce the intensity of hot flashes, night sweats, and vaginal dryness, and helps prevent bone loss that can lead to osteoporosis.
Common Dosages
- 0.025 mg/day
- 0.0375 mg/day
- 0.05 mg/day
- 0.075 mg/day
- 0.1 mg/day
Each patch is worn for 7 days before being replaced with a new patch.
Typical Dosing
- For treating menopausal symptoms, the typical starting dose is 0.025 mg/day or 0.05 mg/day, applied once weekly.
- The patch should be applied to a clean, dry area on the lower abdomen or buttocks and replaced every 7 days.
- Dosage may be adjusted based on individual response and symptom control.
Typical Dosing
FDA Approved Indications
- Treatment of moderate to severe vasomotor symptoms associated with menopause (e.g., hot flashes, night sweats)
- Treatment of vulvar and vaginal atrophy due to menopause
- Prevention of postmenopausal osteoporosis
Who Shouldn't Take Lyllana?
- Undiagnosed abnormal vaginal bleeding
- Active or past history of breast cancer
- Estrogen-dependent cancers (e.g., uterine or ovarian cancer)
- Liver disease
- Known hypersensitivity to estradiol or any of the components in the patch
- History of blood clots, stroke, or heart attack
- Known or suspected pregnancy
Advice From The Pharmacist
- Apply the Lyllana patch to clean, dry skin on the lower abdomen or buttocks, avoiding the breast area. Rotate the application site to avoid skin irritation.
- Make sure the patch is securely in place, but avoid areas that may rub against clothing. If the patch falls off, you can reapply it or replace it with a new one.
- Regularly check your skin for signs of irritation or allergic reactions at the application site. If irritation occurs, consult your healthcare provider.
- If you have not had a hysterectomy, you may need to take a progestin with Lyllana to reduce the risk of endometrial cancer.
- Store the patches at room temperature, away from moisture and heat.
Side Effects of Lyllana
Common Side Effects
- Skin irritation or redness at the patch site
- Breast tenderness
- Nausea
- Headache
- Bloating
- Weight changes
Uncommon/Severe Side Effects
- Blood clots (leg pain, swelling, shortness of breath)
- Stroke (sudden vision changes, slurred speech, or weakness on one side of the body)
- Breast cancer
- Uterine cancer (if used without progestin in women with an intact uterus)
- Liver problems (yellowing of the skin or eyes, severe abdominal pain)
Risks and Warnings of Lyllana
- Cardiovascular Risks: Estrogen therapy increases the risk of blood clots, stroke, and heart attack, particularly in women over the age of 60 or those with risk factors such as smoking or obesity.
- Endometrial Cancer: Women who still have a uterus should take a progestin in combination with Lyllana to reduce the risk of endometrial cancer.
- Breast Cancer: Prolonged use of estrogen therapy may increase the risk of breast cancer. Women should regularly undergo breast exams and mammograms while on HRT.
- Liver Damage: Estrogen therapy has been associated with liver problems, especially in women with pre-existing liver conditions. Symptoms such as jaundice or abdominal pain should be reported immediately.
Interactions with Lyllana
Common Drug Interactions
- Grapefruit juice: May increase estradiol levels and enhance side effects.
- Antiepileptic drugs (e.g., carbamazepine, phenytoin): May decrease the effectiveness of Lyllana by increasing estradiol metabolism.
- Antibiotics (e.g., rifampin): May reduce the effectiveness of Lyllana by increasing estradiol clearance.
- Blood thinners (e.g., warfarin): Estrogen can affect the action of blood thinners and increase the risk of blood clots.
Alternatives to Lyllana
- Vivelle-Dot: Another transdermal estradiol patch used for similar indications.
- Climara: A once-weekly estradiol patch that delivers similar hormone replacement.
- Premarin: A conjugated estrogen tablet used for menopausal symptoms and osteoporosis prevention.
- Estrace: An oral estradiol tablet for managing menopause symptoms.
