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Lyleq
Lyleq is the brand name for norethindrone, a progestin-only birth control pill (also known as the "mini-pill"). It is used to prevent pregnancy by thickening cervical mucus, inhibiting sperm movement, and thinning the uterine lining, which makes it more difficult for an egg to be fertilized or implanted. Lyleq is often prescribed for women who cannot tolerate estrogen-containing contraceptives or those who are breastfeeding.
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Frequently Asked Questions
How effective is Lyleq at preventing pregnancy?
When taken correctly, Lyleq is more than 99% effective at preventing pregnancy. However, its effectiveness decreases if pills are missed or not taken at the same time each day.
Can I take Lyleq while breastfeeding?
Yes, Lyleq is considered safe for use while breastfeeding and does not affect milk production like combination estrogen-progestin contraceptives can.
What should I do if I miss a dose of Lyleq?
If you miss a dose by more than 3 hours, take the missed pill as soon as you remember and use a backup method of contraception for the next 48 hours. Continue taking the next pill at your usual time.
Does Lyleq protect against sexually transmitted infections (STIs)?
No, Lyleq does not protect against STIs. Using condoms in addition to Lyleq can help protect against infections.
Can I use Lyleq if I have a history of blood clots?
Lyleq is considered a safer option for women with a history of blood clots compared to combination pills that contain estrogen, as progestin-only pills carry a lower risk of blood clot formation. However, you should consult your healthcare provider if you have a history of blood clots.
Comprehensive Drug Guide
How Does Lyleq Work?
Lyleq works primarily by thickening cervical mucus, which prevents sperm from reaching the egg. It also alters the lining of the uterus to prevent implantation of a fertilized egg. Unlike combination birth control pills that also suppress ovulation, ovulation may still occur in some women using Lyleq, but the other mechanisms provide effective pregnancy prevention.
Common Dosages
- 0.35 mg oral tablets taken once daily
The typical dosing is one tablet every day, at the same time each day, without breaks between pill packs.
Typical Dosing
- For contraception: The dose is 1 tablet daily, taken at the same time each day, without any breaks between pill packs. It is important to take Lyleq consistently to maintain its effectiveness in preventing pregnancy.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women.
- Birth control for women who cannot take estrogen-containing contraceptives due to health risks, such as those who are breastfeeding or at risk of blood clots.
Who Shouldn't Take Lyleq?
- Known pregnancy.
- Undiagnosed abnormal vaginal bleeding.
- Liver disease or liver tumors.
- Known or suspected breast cancer or other progestin-sensitive cancers.
- Hypersensitivity to norethindrone or any of the components in the tablet.
Advice From The Pharmacist
- Take Lyleq at the same time every day. If you miss a pill by more than 3 hours, use a backup method of contraception, such as condoms, for the next 48 hours.
- Unlike combination birth control pills, there is no pill-free week. You will take a pill every day, even during your period.
- Spotting or irregular bleeding is common, especially during the first few months of use, but this usually improves over time.
- Lyleq is safe for use while breastfeeding.
- If you miss a dose, take it as soon as you remember, even if it means taking two pills in one day. Then, continue taking the next pill at your regular time.
Side Effects of Lyleq
Common Side Effects
- Irregular menstrual periods or spotting
- Nausea
- Headache
- Breast tenderness
- Mood changes
- Acne
Uncommon/Severe Side Effects
- Severe abdominal pain
- Chest pain or shortness of breath
- Severe headaches or migraines
- Vision problems
- Jaundice (yellowing of the skin or eyes)
Risks and Warnings of Lyleq
- Missed Doses: Missing doses or not taking Lyleq at the same time each day significantly reduces its effectiveness and increases the risk of pregnancy. If a pill is missed by more than 3 hours, a backup method of contraception should be used for at least 48 hours.
- Breast Cancer Risk: Women with a history of breast cancer should not use Lyleq, as progestin-only pills may increase the risk of cancer recurrence.
- Ectopic Pregnancy: While rare, progestin-only pills like Lyleq slightly increase the risk of ectopic pregnancy (a pregnancy outside the uterus). If you experience severe abdominal pain, seek medical attention immediately.
Interactions with Lyleq
Common Drug Interactions
- Antiepileptic drugs (e.g., carbamazepine, phenytoin): These medications can decrease the effectiveness of Lyleq by speeding up the metabolism of norethindrone.
- Rifampin: An antibiotic that can reduce the effectiveness of hormonal contraceptives like Lyleq.
- St. John's wort: An herbal supplement that can reduce the effectiveness of Lyleq.
- Antiretroviral drugs: Certain HIV medications can interfere with Lyleq's effectiveness.
Alternatives to Lyleq
- Slynd (drospirenone): Another progestin-only pill that may be used as an alternative to Lyleq.
- Nexplanon: A long-acting, progestin-only contraceptive implant that lasts up to three years.
- Depo-Provera (medroxyprogesterone): A progestin-only contraceptive injection administered every three months.
- Mirena: A progestin-releasing intrauterine device (IUD) that provides long-term contraception for up to five years.
