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LoSeasonique
LoSeasonique is a combination oral contraceptive that contains two hormones: ethinyl estradiol (an estrogen) and levonorgestrel (a progestin). It is used to prevent pregnancy and is unique because it allows for extended-cycle contraception, meaning women take active hormone pills for 84 consecutive days followed by a week of low-dose estrogen, resulting in only four periods per year. In addition to preventing pregnancy, LoSeasonique may be used to treat acne, regulate menstrual cycles, and reduce the frequency and intensity of menstrual-related symptoms, such as cramps and premenstrual syndrome (PMS).
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Frequently Asked Questions
How effective is LoSeasonique at preventing pregnancy?
LoSeasonique is more than 99% effective at preventing pregnancy when taken correctly. However, missing pills or taking them inconsistently can reduce its effectiveness.
How effective is LoSeasonique at preventing pregnancy?
LoSeasonique is more than 99% effective at preventing pregnancy when taken correctly. However, missing pills or taking them inconsistently can reduce its effectiveness.
How effective is LoSeasonique at preventing pregnancy?
LoSeasonique is more than 99% effective at preventing pregnancy when taken correctly. However, missing pills or taking them inconsistently can reduce its effectiveness.
How effective is LoSeasonique at preventing pregnancy?
LoSeasonique is more than 99% effective at preventing pregnancy when taken correctly. However, missing pills or taking them inconsistently can reduce its effectiveness.
Can I use LoSeasonique to skip periods altogether?
LoSeasonique is designed to reduce the frequency of periods to just four per year. While some spotting may occur, it is not typically used to completely eliminate periods.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at the usual time. If you miss two or more pills, follow the instructions in the package insert and use backup contraception (e.g., condoms) for the next 7 days.
What should I do if I miss a pill?
If you miss one active pill, take it as soon as you remember and take the next pill at the usual time. If you miss two or more pills, follow the instructions in the package insert and use backup contraception (e.g., condoms) for the next 7 days.
Can LoSeasonique help with menstrual cramps?
Yes, LoSeasonique can help reduce menstrual cramps by minimizing the number of periods you have each year and regulating your hormone levels.
Is LoSeasonique safe for long-term use?
LoSeasonique is considered safe for long-term use under the supervision of a healthcare provider. Regular check-ups are important to monitor for any potential risks, such as high blood pressure or liver issues.
Comprehensive Drug Guide
How Does LoSeasonique Work?
- Preventing ovulation: The hormones stop the release of an egg from the ovaries.
- Thickening cervical mucus: This makes it more difficult for sperm to enter the uterus and fertilize an egg.
- Altering the uterine lining: The lining of the uterus is less receptive to a fertilized egg, reducing the likelihood of implantation.
By maintaining consistent hormone levels over an extended period, LoSeasonique reduces the frequency of menstrual periods to just four per year.
Common Dosages
- 84 active tablets: Containing 0.10 mg of levonorgestrel and 0.02 mg of ethinyl estradiol.
- 7 placebo tablets: Containing 0.01 mg of ethinyl estradiol (low-dose estrogen to reduce withdrawal symptoms).
Typical Dosing
- Take 1 active pill daily for 84 consecutive days, followed by 1 low-dose estrogen pill daily for 7 days.
- The pack is designed to result in a menstrual period once every three months.
Typical Dosing
FDA Approved Indications
- Preventing pregnancy
- Reducing the frequency of menstrual periods (from monthly to every three months)
- Regulating menstrual cycles
- Reducing the severity of menstrual symptoms such as cramping and heavy bleeding
- Treating moderate acne in women who desire oral contraception
Who Shouldn't Take LoSeasonique?
- A history of blood clots or deep vein thrombosis (DVT)
- Uncontrolled high blood pressure
- Liver disease or liver tumors
- Breast cancer or other estrogen/progestin-sensitive cancers
- Migraine headaches with aura
- Known hypersensitivity to ethinyl estradiol or levonorgestrel
- Smokers over the age of 35, due to an increased risk of cardiovascular events
Advice From The Pharmacist
- Take LoSeasonique at the same time every day for maximum effectiveness. If you miss a pill, follow the instructions provided in the package insert or contact your healthcare provider for guidance.
- Backup contraception (e.g., condoms) should be used if you miss two or more pills or start the pack late, especially in the first cycle.
- LoSeasonique does not protect against sexually transmitted infections (STIs). Use condoms to reduce the risk of STIs.
- Some medications, such as antibiotics and antiepileptics, can reduce the effectiveness of LoSeasonique. Inform your healthcare provider about all medications and supplements you are taking.
- Spotting or breakthrough bleeding may occur during the first few cycles as your body adjusts to the extended regimen. This usually decreases over time.
Side Effects of LoSeasonique
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Breakthrough bleeding or spotting
- Weight changes
- Mood changes
Uncommon/Severe Side Effects
- Blood clots (leg pain, swelling, shortness of breath)
- Stroke (sudden vision changes, difficulty speaking, or weakness on one side of the body)
- Liver problems (yellowing of the skin or eyes, severe abdominal pain)
- High blood pressure
Risks and Warnings of LoSeasonique
- Blood Clots: Combination oral contraceptives like LoSeasonique increase the risk of blood clots, particularly in women who smoke, are overweight, or have a history of clotting disorders.
- Cardiovascular Risks: The risk of heart attack or stroke is higher in women over 35 who smoke. Women who smoke should consider alternative methods of contraception.
- Liver Damage: Estrogen-containing contraceptives can cause liver problems, including benign liver tumors. Monitor liver function if there is a history of liver disease.
- Cancers: There may be a slight increased risk of breast and cervical cancers with long-term use of hormonal contraceptives.
Interactions with LoSeasonique
Common Drug Interactions
- Antibiotics (e.g., rifampin): May reduce the effectiveness of LoSeasonique.
- Antiepileptic drugs (e.g., carbamazepine, phenytoin): May decrease contraceptive efficacy.
- St. John’s Wort: Can lower the effectiveness of LoSeasonique, increasing the risk of unintended pregnancy.
- HIV medications: Certain antiretrovirals can interfere with the effectiveness of hormonal contraceptives.
Alternatives to LoSeasonique
- Seasonale: A similar extended-cycle contraceptive with the same active ingredients, but with slightly different dosing.
- Seasonique: A similar extended-cycle contraceptive that provides continuous low-dose estrogen during the last week to minimize withdrawal symptoms.
- NuvaRing: A vaginal ring that delivers a continuous dose of hormones over a 3-week period, followed by a ring-free week.
- Depo-Provera: A progestin-only injectable contraceptive given once every 3 months.
- Mirena (IUD): A long-term intrauterine device that releases progestin to prevent pregnancy.
