You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Losartan Potassium-HCTZ
Losartan Potassium-HCTZ is a combination medication that includes losartan, an angiotensin II receptor blocker (ARB), and hydrochlorothiazide (HCTZ), a thiazide diuretic. This combination is primarily used to treat hypertension (high blood pressure). By using both medications, it helps to lower blood pressure more effectively than either agent alone, reducing the risk of cardiovascular events.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Losartan Potassium-HCTZ ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Losartan Potassium-HCTZ to lower blood pressure?
Most patients may start to see improvements in their blood pressure within a week, but it can take up to several weeks for the full effects to be realized.
Can I take Losartan Potassium-HCTZ with food?
Losartan Potassium-HCTZ can be taken with or without food, but it is best to take it consistently in the same way.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while taking Losartan Potassium-HCTZ?
There are no strict dietary restrictions, but it’s advisable to monitor your potassium intake and maintain a balanced diet.
Is it safe to drink alcohol while taking Losartan Potassium-HCTZ?
It is advisable to limit alcohol consumption, as it can enhance the blood pressure-lowering effects of Losartan Potassium-HCTZ and increase the risk of side effects. Always consult your healthcare provider for specific guidance.
Comprehensive Drug Guide
How Does Losartan Potassium-HCTZ Work?
- Losartan works by blocking the action of angiotensin II, a substance that constricts blood vessels, thereby relaxing blood vessels and reducing blood pressure.
- Hydrochlorothiazide helps to lower blood pressure by promoting the excretion of sodium and water through urine, which decreases blood volume and further lowers blood pressure.
Common Dosages
- Combination tablets: typically containing 50 mg of losartan and 12.5 mg of hydrochlorothiazide, or 100 mg of losartan and 25 mg of hydrochlorothiazide.
Typical Dosing
- The usual starting dose for hypertension is 50 mg/12.5 mg once daily, which may be adjusted based on blood pressure response, with a maximum dose of 100 mg/25 mg daily.
Typical Dosing
FDA Approved Indications
- Hypertension: to lower blood pressure in adults and children.
- Heart failure: as part of a broader treatment strategy to improve cardiovascular outcomes.
Who Shouldn't Take Losartan Potassium-HCTZ?
- Known hypersensitivity to losartan, hydrochlorothiazide, or any component of the formulation.
- Severe renal impairment.
- Pregnancy, especially in the second and third trimesters.
Advice From The Pharmacist
- Take Losartan Potassium-HCTZ exactly as prescribed, preferably at the same time each day.
- Monitor your blood pressure regularly to ensure the medication is effective.
- Be aware of signs of dehydration, such as dizziness or fainting, especially when standing up quickly.
- Inform your healthcare provider of any other medications you are taking, as interactions may occur.
Side Effects of Losartan Potassium-HCTZ
Common Side Effects
- Dizziness or lightheadedness
- Cough (less common with losartan compared to other ARBs)
- Fatigue
- Increased urination
Uncommon/Severe Side Effects
- Allergic reactions (rash, swelling, difficulty breathing)
- Elevated potassium levels (hyperkalemia)
- Kidney dysfunction
Risks and Warnings of Losartan Potassium-HCTZ
- Hypotension: Especially in patients who are salt-depleted or volume-depleted, hypotension can occur. Monitor blood pressure closely.
- Electrolyte Imbalance: Regular blood tests may be necessary to monitor potassium and renal function during treatment.
- Pregnancy: This medication should not be used during pregnancy as it can harm the developing fetus.
Interactions with Losartan Potassium-HCTZ
Common Drug Interactions
- Diuretics: Combining with other diuretics may increase the risk of hypotension and electrolyte imbalances.
- NSAIDs: Nonsteroidal anti-inflammatory drugs can reduce the antihypertensive effect of losartan.
- Potassium Supplements: Caution is advised when taking potassium supplements or potassium-sparing diuretics, as this may lead to hyperkalemia.
Alternatives to Losartan Potassium-HCTZ
- Amlodipine: A calcium channel blocker used to treat high blood pressure.
- Valsartan: An angiotensin receptor blocker (ARB) that can be used for similar indications as losartan.
- Beta-Blockers: Such as metoprolol for managing hypertension and heart conditions.
