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Lopid
Lopid, also known as gemfibrozil, is a type of medication that helps reduce levels of "bad cholesterol"" (LDL) and fats (triglycerides) and raise ""good cholesterol"" (HDL) in the blood. It belongs to a group of drugs known as fibrates. This medication can help prevent pancreas disease (pancreatitis) and atherosclerosis (clogged arteries). Certain side effects include stomach upset
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Frequently Asked Questions
Can I just stop taking Lopid after my symptoms are gone?
Never discontinue Lopid usage without consulting your doctor. Stopping the medication suddenly could elevate your cholesterol levels again and put you at risk.
Can I take Lopid if I have diabetes?
Certainly, Lopid has been known to affect blood sugar levels. Diabetics should monitor their sugar levels closely while taking this medication.
Can Lopid cause weight gain?
Weight gain is not a typical side effect of Lopid. However, if you notice any unexpected weight changes, consult with your healthcare provider.
I missed a dose of Lopid, what should I do?
If it's near the time of your next dose, skip the missed dose and resume your usual dosing schedule. However, if there's ample time before your next dose, take the missed dose. Never double up the doses.
Comprehensive Drug Guide
How Does Lopid Work?
gallstones
What is Lopid Used For?
and muscle problems
Common Dosages
but your healthcare professional will generally oversee these risks."
Typical Dosing
FDA Approved Indications
- Lopid is a lipidregulating agent that inhibits peroxisome proliferatoractivated receptor (PPAR) alpha which regulates lipid metabolism. It decreases serum triglycerides and increases HDL cholesterol.
Off-Label Uses
- FDA indications: Lopid is principally used to manage adult patients with severe hypertriglyceridemia. It's also used to lower the risk of developing pancreatitis and progress of coronary atherosclerosis (plaque buildup in the arteries).
- Offlabel uses: It's even been used to decrease the risk of coronary heart disease, enhance diabetic control in dyslipidemia associated with diabetes, and help patients with acute coronary syndrome.
Pediatric Dosing
- Tablets: 600mg
Who Shouldn't Take Lopid?
- Hypertriglyceridemia: 600mg twice daily, 30 minutes before the morning and evening meals.
Advice From The Pharmacist
- Acute coronary syndrome: the dosage depends on the healthcare provider's discretion.
Side Effects of Lopid
Uncommon/Severe Side Effects
- Those who are allergic to gemfibrozil.
- Persons who recently had liver or gallbladder disease.
- Patients with severe kidney disease.
- Individuals who are also taking repaglinide.
- Pregnant or breastfeeding women.
- Individuals suffering from active liver disease including primary biliary cirrhosis.
- Persons with significant or unexplained persistent elevations in serum transaminases.
Risks and Warnings of Lopid
- Always take Lopid 30 minutes before breakfast and dinner.
- Do not take Lopid if you are allergic to gemfibrozil.
- Check with your doctor before eating large amounts of certain fruits while taking Lopid.
- Report unusual muscle pain or weakness to your doctor right away.
- Lopid can lead to gallstones, so regular checkups are important.
- Don't stop taking the medication abruptly without consulting your doctor.
Interactions with Lopid
Common Drug Interactions
- Stomach upset or abdominal pain.
- Diarrhea or indigestion.
- You may also experience headaches or dizziness.
Common Food Interactions
- Uncommon side effects:
- Muscle pain or tenderness.
- Unusual tiredness or weakness.
- Irregular heartbeat.
- Yellowing of the skin or eyes.
- Rare side effects:
- Skin rash or itching.
- Fever or sore throat.
- Severe side effects:
- Unusual weight loss or gain.
- Dark urine or lightcolored stools.
- Numbness of arms or legs.
- Persistent nausea or vomiting.
- Severe stomach or abdominal pain.
Alternatives to Lopid
- Individuals with liver or kidney disease should avoid taking Lopid as it can cause further complications.
- Those with a known allergic reaction to gemfibrozil should refrain from taking Lopid.
- High cholesterol and heart disease patients should work closely with their healthcare providers to monitor blood cholesterol levels while on medication.
- Pregnant or breastfeeding women should consult with their healthcare provider before commencing Lopid.
- Patients need to understand that muscle problems can occur while taking this medication, and immediate medical attention should be sought if muscle pain or weakness occurs.
- Persistent or severe abdominal pain should be reported to the healthcare provider as it can indicate the presence of gallstones.
