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Locoid
Locoid, the brand name for hydrocortisone butyrate, is a topical corticosteroid used to treat inflammatory skin conditions such as eczema, dermatitis, psoriasis, and allergic reactions. It works by reducing inflammation, itching, and redness in affected areas of the skin. Locoid is considered a medium-potency corticosteroid, making it suitable for treating a wide range of mild to moderate skin conditions.
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Frequently Asked Questions
How long can I use Locoid?
Locoid should be used for the shortest duration possible to control symptoms. Prolonged use can increase the risk of side effects such as skin thinning. Your doctor will advise on the appropriate length of treatment.
Can I use Locoid on my face?
Locoid should not be used on the face unless specifically directed by your healthcare provider, as the skin on the face is thinner and more prone to side effects like skin thinning or acne-like eruptions.
What should I do if I miss a dose of Locoid?
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed application and continue with your regular dosing schedule. Do not apply extra medication to make up for the missed dose.
Can I use Locoid on children?
Locoid can be used in children, but with caution. Children are more sensitive to the effects of corticosteroids, and long-term use can lead to growth suppression and other systemic effects. Always follow your doctor’s instructions closely when using Locoid on children.
Can I use Locoid for a fungal or bacterial infection?
No, Locoid is not effective for treating fungal or bacterial infections. It is designed to treat inflammatory skin conditions. If you suspect an infection, consult your doctor for the appropriate treatment.
Comprehensive Drug Guide
How Does Locoid Work?
Locoid works by mimicking the effects of corticosteroids, naturally occurring hormones produced by the adrenal glands. It acts on the immune system to reduce the release of inflammatory substances that cause redness, swelling, and itching. By suppressing the immune response in the skin, Locoid helps to control inflammation and provide relief from symptoms like itching and irritation.
Common Dosages
- 0.1% topical cream, ointment, lotion, and solution
The typical dosage involves applying a thin layer of Locoid to the affected area once or twice daily. The exact duration of treatment depends on the severity of the condition and response to therapy.
Typical Dosing
- For inflammatory skin conditions: Apply a thin layer to the affected area once or twice daily, depending on the severity of the condition and the doctor's recommendation. Use the lowest effective dose for the shortest duration to minimize side effects.
- Avoid using Locoid on the face, groin, or underarms unless directed by your healthcare provider.
Typical Dosing
FDA Approved Indications
- Atopic dermatitis (eczema)
- Contact dermatitis
- Seborrheic dermatitis
- Psoriasis
- Allergic skin reactions
- Other inflammatory skin conditions that respond to topical corticosteroids
Who Shouldn't Take Locoid?
- Known hypersensitivity or allergy to hydrocortisone butyrate or any of the components of the formulation.
- Viral skin infections (e.g., herpes, chickenpox)
- Fungal skin infections (e.g., athlete's foot, ringworm) unless combined with an antifungal treatment.
- Tuberculosis of the skin
Advice From The Pharmacist
- Apply a thin layer of Locoid to the affected area and gently rub it in. Do not cover the area with a bandage or dressing unless directed by your doctor, as this may increase the risk of side effects.
- Do not apply Locoid to broken skin or infected areas unless prescribed for such use, and avoid using it on large areas of skin for an extended period.
- Wash your hands before and after applying Locoid unless you are treating your hands.
- Use caution when applying near the eyes or mouth; if it accidentally gets into these areas, rinse thoroughly with water.
Side Effects of Locoid
Common Side Effects
- Burning, itching, or stinging at the application site
- Dryness or flaking of the skin
- Thinning of the skin (with long-term use)
Uncommon/Severe Side Effects
- Stretch marks or skin discoloration in the treated area
- Increased risk of infection in the treated area
- Adrenal suppression (when used over large areas or for extended periods)
- Allergic reactions such as severe rash, swelling, or difficulty breathing
Risks and Warnings of Locoid
- Skin Thinning: Prolonged use of Locoid can cause thinning of the skin, especially in sensitive areas like the face, groin, and underarms. Limit use in these areas unless specifically instructed by your doctor.
- Adrenal Suppression: High doses or long-term use of topical corticosteroids can lead to adrenal suppression, where the body’s production of natural corticosteroids is reduced. This is more likely when the medication is used over large areas of the body or under occlusive dressings.
- Infection Risk: Because Locoid suppresses the immune response, using it on infected skin or open wounds can lead to worsening infections.
Interactions with Locoid
Common Drug Interactions
- Locoid has minimal systemic absorption, so drug interactions are rare when used as prescribed. However, certain situations may increase absorption, such as applying the medication over large areas of skin or under occlusive dressings. Always inform your healthcare provider about any other medications you are using, including other topical treatments.
Alternatives to Locoid
- Hydrocortisone: A lower-potency over-the-counter corticosteroid used for mild inflammatory skin conditions.
- Betamethasone (Diprolene): A stronger topical corticosteroid for treating more severe skin conditions.
- Clobetasol (Clobex): A high-potency corticosteroid used for severe inflammatory conditions.
- Tacrolimus (Protopic): A non-steroidal topical immunomodulator used to treat eczema and other inflammatory skin conditions in patients who cannot tolerate corticosteroids.
