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Lidocaine-Tetracaine

Lidocaine-tetracaine is a topical anesthetic combination that includes lidocaine and tetracaine. It is used to provide localized pain relief for various dermatological procedures, including minor surgeries, wound care, and the numbing of skin prior to needle insertions.

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Frequently Asked Questions

How long does it take for lidocaine-tetracaine to start working?
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Lidocaine-tetracaine typically begins to numb the area within 30 minutes of application, with maximum effect occurring around 1 hour.

Can I take lidocaine-tetracaine with other medications?
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Always consult your healthcare provider before combining lidocaine-tetracaine with other medications, especially topical products.

What should I do if I miss a dose of lidocaine-tetracaine?
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If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply extra to compensate.

Is it safe to use lidocaine-tetracaine during pregnancy?
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Lidocaine-tetracaine should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.

Can lidocaine-tetracaine cause weight gain?
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Weight gain is not commonly associated with lidocaine-tetracaine. Any significant changes in weight should be discussed with a healthcare provider.

Comprehensive Drug Guide

How Does Lidocaine-Tetracaine Work?

Lidocaine and tetracaine work by blocking sodium channels in the neuronal membrane, inhibiting the initiation and conduction of nerve impulses. This results in localized numbness in the area where it is applied, effectively alleviating pain during procedures.



What is Lidocaine-Tetracaine Used For?


Common Dosages

  • Topical cream or gel: Common concentration is 2.5% lidocaine and 2.5% tetracaine.

Typical Dosing

  • The usual dosage involves applying a sufficient amount of the cream or gel to the affected area 30 to 60 minutes before the procedure, allowing it to remain in place to achieve maximum effect.

Typical Dosing

FDA Approved Indications

  • Topical anesthesia for minor surgical procedures.
  • Numbing skin before injections or other invasive procedures.

Who Shouldn't Take Lidocaine-Tetracaine?

  • Known hypersensitivity to lidocaine, tetracaine, or any components of the formulation
  • Open wounds or damaged skin unless specifically directed by a healthcare provider


Advice From The Pharmacist

  • Patients should be advised to apply lidocaine-tetracaine only to intact skin and to wash their hands after application to avoid contact with the eyes or mucous membranes.
  • Discuss the importance of not exceeding the recommended dosage and duration of use to avoid potential side effects.
  • Encourage patients to report any signs of irritation or allergic reactions.


Side Effects of Lidocaine-Tetracaine

Common Side Effects

  • Localized skin irritation
  • Redness or swelling at the application site
  • Burning or stinging sensation upon application


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Systemic toxicity if absorbed in large amounts or used improperly


Risks and Warnings of Lidocaine-Tetracaine

  • Local Irritation: Monitor for any signs of irritation or allergic reaction, especially during initial use.
  • Caution in Patients with Cardiac Conditions: Use with caution in patients with a history of heart disease, as high doses may affect cardiac function.

Interactions with Lidocaine-Tetracaine

Common Drug Interactions

Other Topical Anesthetics: Avoid concurrent use with other local anesthetics to reduce the risk of systemic toxicity.

Alternatives to Lidocaine-Tetracaine

  • Other Topical Anesthetics: Such as benzocaine or other anesthetic formulations for similar applications.
  • Oral Pain Relief: Over-the-counter analgesics like acetaminophen or ibuprofen for systemic pain management.