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Levulan Kerastick
Levulan Kerastick (aminolevulinic acid) is a topical medication used primarily for the treatment of actinic keratosis, a precancerous skin condition caused by sun damage. When applied to the skin, it is converted to protoporphyrin IX, which accumulates in abnormal cells and makes them more sensitive to light.
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Frequently Asked Questions
How long does it take for Levulan Kerastick to work?
Patients may begin to notice improvements in their skin condition within 2 to 4 weeks after treatment.
Can I take Levulan Kerastick with other medications?
Always consult your healthcare provider before combining Levulan Kerastick with other medications, especially topical products.
What should I do if I miss a dose of Levulan Kerastick?
If you miss the application, follow the prescribed protocol as soon as possible. Consult your healthcare provider if unsure about rescheduling treatment.
Is it safe to use Levulan Kerastick during pregnancy?
Levulan Kerastick should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Levulan Kerastick cause weight gain?
Weight gain is not commonly associated with Levulan Kerastick, as it is a topical treatment. Any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Levulan Kerastick Work?
Levulan Kerastick works by being absorbed by rapidly dividing cells, such as those found in actinic keratosis. After a specific incubation period, the treated area is exposed to blue light (usually with a specific device), which activates the protoporphyrin IX. This leads to the destruction of the abnormal cells through photodynamic therapy.
Common Dosages
Levulan Kerastick is typically available as:
- Single-use applicator containing 20% aminolevulinic acid.
Typical Dosing
- The usual dosage involves applying Levulan Kerastick to the affected area and allowing it to incubate for approximately 14 to 18 hours before exposing the area to blue light for treatment.
Typical Dosing
FDA Approved Indications
- Treatment of actinic keratosis on the face and scalp.
Who Shouldn't Take Levulan Kerastick?
- Known hypersensitivity to aminolevulinic acid or any components of the formulation
- A history of porphyria
Advice From The Pharmacist
- Patients should be instructed on the proper application technique and the importance of following the incubation and light treatment protocols for optimal results.
- Discuss the importance of avoiding sun exposure for at least 48 hours after treatment, as the skin will be more sensitive to light.
- Encourage patients to report any signs of severe irritation or allergic reactions.
Side Effects of Levulan Kerastick
Common Side Effects
- Redness at the application site
- Swelling or blistering
- Burning or stinging sensation
- Scaling or crusting of the skin
Uncommon/Severe Side Effects
Severe allergic reactions (anaphylaxis)
Risks and Warnings of Levulan Kerastick
- Photosensitivity: After treatment, patients should avoid exposure to sunlight or bright indoor light for at least 48 hours to prevent severe skin reactions.
- Skin Reactions: Monitor for any severe or persistent skin reactions following treatment.
Interactions with Levulan Kerastick
Common Drug Interactions
Other Topical Treatments: Consult a healthcare provider before using other topical medications on the treated area to avoid exacerbating irritation.
Alternatives to Levulan Kerastick
- Other Topical Treatments: Such as imiquimod or fluorouracil for actinic keratosis.
- Cryotherapy: A common alternative for treating actinic keratosis.
