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Levoxyl
Levoxyl, the brand name for levothyroxine sodium, is a synthetic form of thyroid hormone used to treat hypothyroidism (underactive thyroid). In individuals with hypothyroidism, the thyroid gland does not produce enough of the hormone thyroxine (T4), which is necessary for regulating the body's metabolism. Levoxyl works by replacing or supplementing the missing thyroid hormone, helping to restore normal thyroid function, reduce symptoms such as fatigue, weight gain, and depression, and maintain overall metabolic health.
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Frequently Asked Questions
What should I do if I miss a dose of Levoxyl?
Take the missed dose as soon as you remember, but skip it if it’s close to your next scheduled dose. Do not double up on doses.
How long does it take for Levoxyl to start working?
It may take several weeks for Levoxyl to fully restore thyroid hormone levels and for symptoms of hypothyroidism to improve.
Can I take Levoxyl with food?
No, Levoxyl should be taken on an empty stomach at least 30 to 60 minutes before eating to ensure proper absorption.
Do I need to take Levoxyl for life?
In most cases of hypothyroidism, lifelong therapy is required to maintain normal thyroid function, though regular monitoring and dose adjustments may be necessary.
Can Levoxyl cause weight loss?
Levoxyl may cause weight loss in individuals who are treated for hypothyroidism, but it is not a weight loss medication and should not be used for that purpose.
Comprehensive Drug Guide
How Does Levoxyl Work?
Levoxyl works by replacing the body's natural thyroid hormone, thyroxine (T4). Once absorbed into the bloodstream, it is converted into triiodothyronine (T3), the active form of thyroid hormone. T3 helps regulate various bodily functions, including metabolism, energy production, and temperature regulation. By restoring normal thyroid hormone levels, Levoxyl helps reverse the symptoms of hypothyroidism and maintain normal metabolic function.
Common Dosages
Levoxyl is available in a wide range of strengths to allow for precise dosing:
- 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, and 300 mcg tablets.
The dose is individualized based on factors such as age, weight, the severity of hypothyroidism, and response to treatment. Dosing adjustments may be necessary over time to ensure proper thyroid function.
Typical Dosing
For adults with hypothyroidism:
- The typical starting dose for healthy adults is 1.6 mcg/kg/day taken once daily, usually in the morning on an empty stomach.
- In older adults or individuals with heart disease, lower starting doses (e.g., 12.5 mcg to 50 mcg once daily) may be prescribed, with gradual increases based on response.
For children:
- Dosing is determined by weight and age, with frequent monitoring to ensure proper growth and development.
Your healthcare provider will adjust your dose based on regular blood tests to monitor thyroid-stimulating hormone (TSH) levels and ensure the right balance of thyroid hormone.
Typical Dosing
FDA Approved Indications
- Treatment of hypothyroidism (primary, secondary, congenital, or due to other causes).
- Treatment or suppression of goiter (enlarged thyroid gland).
- Adjunct to thyroid cancer treatment: Levoxyl is sometimes used to suppress thyroid-stimulating hormone (TSH) levels in individuals with certain types of thyroid cancer.
Advice From The Pharmacist
- Take Levoxyl once daily in the morning on an empty stomach, at least 30 to 60 minutes before eating or taking other medications, to ensure optimal absorption.
- Avoid taking calcium or iron supplements, antacids, or certain foods (such as soy) within four hours of taking Levoxyl, as these can interfere with its absorption.
- It is important to take Levoxyl at the same time each day.
- Regular blood tests are necessary to monitor your thyroid function, and your dose may be adjusted accordingly.
- Never stop taking Levoxyl without consulting your healthcare provider, as stopping suddenly can result in serious health consequences.
Side Effects of Levoxyl
Common Side Effects
- Weight loss
- Nervousness or anxiety
- Headache
- Increased heart rate (tachycardia)
- Sweating
Uncommon/Severe Side Effects
- Chest pain or irregular heartbeat (indicative of heart issues).
- Signs of overdose, such as confusion, excessive sweating, or shaking.
- Severe allergic reactions (swelling, rash, or difficulty breathing).
Risks and Warnings of Levoxyl
- Levoxyl can cause symptoms of hyperthyroidism (too much thyroid hormone) if taken in excessive doses, leading to increased heart rate, anxiety, weight loss, and sweating.
- Be cautious when starting or adjusting doses, especially if you have heart disease or are an older adult.
- Individuals with osteoporosis should also be monitored carefully, as long-term high doses of thyroid hormone can weaken bones.
- Close monitoring of thyroid function through regular blood tests is essential to avoid complications.
Interactions with Levoxyl
Common Drug Interactions
- Calcium or iron supplements, which can reduce the absorption of levothyroxine.
- Antacids and cholesterol-lowering drugs (such as cholestyramine), which can interfere with absorption.
- Antidepressants and blood thinners (such as warfarin), which may require dose adjustments when used with levothyroxine.
- Soy-containing products or high-fiber diets, which can affect the absorption of Levoxyl.
Alternatives to Levoxyl
- Synthroid (another brand of levothyroxine).
- Levothroid (another brand of levothyroxine).
- Armour Thyroid or Nature-Throid (natural thyroid hormone derived from pigs).
