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Cholestyramine
Cholestyramine is known as a bile acidbinding resin. It is often used to lower high levels of cholesterol in the blood, especially lowdensity lipoprotein (LDL, also known as the "bad cholesterol""). Moreover
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Frequently Asked Questions
Can I drink alcohol while taking Cholestyramine?
Moderate alcohol consumption might increase your triglyceride levels and potentially, your risk of liver damage. It's highly recommended you discuss this with your healthcare provider.
Does Cholestyramine cause constipation?
Yes, constipation is a common side effect of cholestyramine. To help prevent this, eat a highfiber diet, drink six to eight glasses of water each day, and exercise regularly.
Does Cholestyramine cause weight loss?
While weight loss isn't commonly associated with cholestyramine, it may occur if you experience side effects like stomach pain or chronic diarrhea. Consult your doctor if you lose weight while using cholestyramine.
What should I do if I miss a dose of Cholestyramine?
If it's almost time for your next dose, skip the missed one. If there's plenty of time, take it as soon as you remember. But remember, never take two doses at once!
Comprehensive Drug Guide
How Does Cholestyramine Work?
it's used to treat itching caused by a blockage in the bile ducts of the gallbladder. Cholestyramine does cause several side effects
What is Cholestyramine Used For?
including constipation
Common Dosages
stomach pain
Typical Dosing
FDA Approved Indications
- and nausea. But as always
Off-Label Uses
- your doctor will ensure the pros outweigh the cons."
Pediatric Dosing
- Cholestyramine functions as a bile acid sequestrant, binding to bile acids in the intestine, facilitating their excretion in the feces, and thereby reducing circulating cholesterol levels.
Who Shouldn't Take Cholestyramine?
- FDA indications: Cholestyramine is mainly utilized to lower high cholesterol levels. It's also used to manage itching caused by partial biliary obstruction.
- Offlabel uses: Physicians might prescribe it for diarrhea resulting from bile acid malabsorption.
Advice From The Pharmacist
- Powder: 4 grams of cholestyramine resin per 9 grams of powder
Side Effects of Cholestyramine
Common Side Effects
- High cholesterol: 4 grams orally once or twice daily. The dose may be increased up to 8 to 16 grams daily, divided into two doses.
- Itching caused by biliary obstruction: The dose is tailored to the specific needs of each patient.
Uncommon/Severe Side Effects
- Diarrhea due to bile acid malabsorption: The dose range is typically the same as for high cholesterol.
Interactions with Cholestyramine
Common Drug Interactions
- Anyone who's already dealing with total biliary obstruction.
- If you've been diagnosed with phenylketonuria, owing to the aspartame content in some formulations of cholestyramine.
- Individuals suffering from severe constipation.
Common Food Interactions
- Engage in daily physical exercise and adhere to a diet low in cholesterol and saturated fats.
- Cholestyramine should typically be taken 1 hour before or 4 to 6 hours after taking other medications, as it can interfere with their absorption.
- The powder must be mixed with water or other noncarbonated beverages before intake.
- Regular intake at the same time each day would fetch the best results.
- It's normal to see a tangible effect on your cholesterol levels only after a month.
- Unexpected bleeding or bruising, loss of appetite, stomach pain, claycolored stools, or severe constipation? Get in touch with your healthcare provider immediately.
Alternatives to Cholestyramine
- Common side effects:
- Constipation and stomach pain.
- Nausea or vomiting.
- Heartburn.
- Unexpected weight loss.
- Black, tarry stools.
- Uncommon/Rare side effects:
- Swelling in your ankles or feet.
- Blood in your urine.
- Hemorrhoids.
- Skin rash or itching.
- Severe stomach/abdominal pain.
