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Lessina
Lessina is a combination oral contraceptive pill containing ethinyl estradiol (an estrogen) and levonorgestrel (a progestin). It is primarily used for preventing pregnancy. In addition to contraception, Lessina may help with regulating menstrual cycles, reducing menstrual cramps, and treating acne in women who also desire oral contraception. By maintaining consistent hormone levels, Lessina prevents ovulation and creates changes in the cervical mucus and uterine lining, making it more difficult for sperm to reach an egg and for a fertilized egg to attach to the uterus.
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Frequently Asked Questions
How effective is Lessina at preventing pregnancy?
Lessina is over 99% effective when taken correctly. However, missing pills or inconsistent use can reduce its effectiveness.
What should I do if I miss a pill?
If you miss a pill, take it as soon as you remember and take the next pill at the usual time. If you miss two or more pills, follow the instructions in the package insert and use backup contraception (e.g., condoms) for the next 7 days.
Can I use Lessina to regulate my menstrual cycle?
Yes, Lessina can help regulate your period and reduce the severity of menstrual cramps and other symptoms related to menstruation.
Can Lessina be used to treat acne?
Yes, Lessina is sometimes used to treat mild to moderate acne in women who also desire oral contraception. The hormones in Lessina can reduce the activity of sebaceous glands, leading to clearer skin.
Is Lessina safe for long-term use?
Yes, Lessina is safe for long-term use under the supervision of a healthcare provider. However, regular check-ups are important to monitor for any potential side effects, such as high blood pressure or liver issues.
Comprehensive Drug Guide
How Does Lessina Work?
- Preventing ovulation: The hormones stop the release of an egg from the ovaries.
- Thickening cervical mucus: This makes it harder for sperm to enter the uterus and fertilize an egg.
- Altering the uterine lining: The lining becomes less receptive to implantation, reducing the likelihood of a fertilized egg attaching to the uterus.
Common Dosages
- 21 active pills: Containing 0.02 mg of ethinyl estradiol and 0.10 mg of levonorgestrel.
- 7 inactive pills: Taken during the last week to allow for a menstrual period.
Typical Dosing
- Take 1 active pill daily for 21 days, followed by 1 inactive pill daily for 7 days. A period usually occurs during the week of inactive pills.
- Start the next pack immediately after finishing the inactive pills to maintain contraceptive protection.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy
- Regulation of menstrual cycles
- Reduction of menstrual cramps
- Management of acne in women who desire oral contraception
Who Shouldn't Take Lessina?
- History of blood clots, deep vein thrombosis (DVT), or pulmonary embolism (PE)
- Uncontrolled high blood pressure
- Liver disease or liver tumors
- Breast cancer or other hormone-sensitive cancers
- Smoking and over the age of 35, due to increased cardiovascular risks
Advice From The Pharmacist
- Take Lessina at the same time every day for maximum effectiveness. If you miss a pill, follow the instructions provided in the package insert or contact your healthcare provider for guidance.
- Backup contraception (e.g., condoms) should be used if you miss two or more pills or start a new pack late.
- Lessina does not protect against sexually transmitted infections (STIs). Use condoms to reduce the risk of STIs.
- Spotting or breakthrough bleeding may occur during the first few months as your body adjusts to the hormones. This is usually temporary.
- Some medications, such as antibiotics or antiepileptics, may reduce the effectiveness of Lessina. Inform your healthcare provider about all medications and supplements you are taking.
Side Effects of Lessina
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Weight changes
- Mood changes
- Spotting or breakthrough bleeding
Uncommon/Severe Side Effects
- Blood clots (leg pain, swelling, shortness of breath)
- Stroke (sudden vision changes, trouble speaking, or weakness on one side of the body)
- Liver issues (yellowing of the skin or eyes, upper stomach pain)
- High blood pressure
Risks and Warnings of Lessina
- Blood Clots: The risk of blood clots is higher in women who take combination oral contraceptives, particularly in those who smoke or are overweight. Women who smoke should avoid using Lessina if they are over 35 years old.
- Cardiovascular Risks: The risk of heart attack or stroke is higher in women over 35 who smoke. These women should consider alternative contraceptive options.
- Liver Damage: Combination oral contraceptives may cause liver damage or benign liver tumors. Regular liver function tests may be required for women with a history of liver issues.
- Breast and Cervical Cancer: Prolonged use of hormonal contraceptives may slightly increase the risk of breast and cervical cancer. Regular screening is recommended.
Interactions with Lessina
Common Drug Interactions
- Antibiotics (e.g., rifampin): May reduce the effectiveness of Lessina, leading to an increased risk of unintended pregnancy.
- Antiepileptic drugs (e.g., carbamazepine, phenytoin): May decrease the contraceptive efficacy of Lessina.
- St. John’s Wort: Can lower the effectiveness of Lessina, increasing the risk of pregnancy.
- HIV medications: Some antiretrovirals may interfere with the effectiveness of oral contraceptives.
Alternatives to Lessina
- Loestrin: A combination oral contraceptive with a different formulation of estrogen and progestin.
- Ortho Tri-Cyclen: A combination contraceptive that varies hormone levels throughout the cycle.
- Depo-Provera: A progestin-only injectable contraceptive given every 3 months.
- IUDs: Intrauterine devices like Mirena or ParaGard provide long-term contraception without daily pills.