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Leena

Leena is a combination oral contraceptive pill that contains two hormones: ethinyl estradiol (an estrogen) and norethindrone (a progestin). It is primarily used for preventing pregnancy by stopping ovulation, thickening cervical mucus, and altering the uterine lining to prevent fertilization or implantation. In addition to contraception, Leena can help regulate menstrual cycles, reduce menstrual cramps, and manage acne in women who also desire birth control.

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Frequently Asked Questions

How effective is Leena at preventing pregnancy?
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Leena is over 99% effective when taken correctly. Missing pills or inconsistent use can reduce its effectiveness.

What should I do if I miss a pill?
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If you miss a pill, take it as soon as you remember and take the next pill at the usual time. If you miss two or more pills, follow the package insert instructions and use backup contraception (e.g., condoms) for the next 7 days.

Can Leena regulate my menstrual cycle?
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Yes, Leena can help regulate your period, reduce menstrual cramps, and make periods lighter and more predictable.

Can Leena help with acne?
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Yes, Leena can help treat mild to moderate acne in women who also desire oral contraception. The hormones in Leena reduce androgen levels, which can decrease acne formation.

Is Leena safe for long-term use?
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Leena is generally safe for long-term use under the supervision of a healthcare provider. Regular check-ups are recommended to monitor for any side effects, such as high blood pressure or liver issues.

Comprehensive Drug Guide

How Does Leena Work?

  1. Prevents ovulation: The hormones stop the release of an egg from the ovaries.
  2. Thickens cervical mucus: This makes it harder for sperm to reach the egg.
  3. Alters the uterine lining: This reduces the likelihood of implantation of a fertilized egg.

Common Dosages

  • 21 active pills: Containing 0.035 mg of ethinyl estradiol and 0.5 mg or 1 mg of norethindrone.
  • 7 inactive pills: Taken during the last week of the cycle to allow for a menstrual period.

Typical Dosing

  • Take 1 active pill daily for 21 days, followed by 1 inactive pill daily for 7 days. A period generally occurs during the week of inactive pills.
  • Begin the next pack immediately after finishing the inactive pills to maintain contraceptive protection.

Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy
  • Regulation of menstrual cycles
  • Reduction of menstrual cramps
  • Management of acne in women who desire oral contraception

Who Shouldn't Take Leena?

  • History of blood clots, deep vein thrombosis (DVT), or pulmonary embolism (PE)
  • Uncontrolled high blood pressure
  • Liver disease or liver tumors
  • Breast cancer or other hormone-sensitive cancers
  • Smoking and over the age of 35, due to increased cardiovascular risks

Advice From The Pharmacist

  • Take Leena at the same time every day to maintain its effectiveness. If you miss a pill, follow the instructions provided in the package insert or consult your healthcare provider.
  • Use backup contraception (e.g., condoms) if you miss two or more pills or start a new pack late.
  • Leena does not protect against sexually transmitted infections (STIs). Use condoms to reduce the risk of STIs.
  • Spotting or breakthrough bleeding may occur during the first few months as your body adjusts to the hormones. This is usually temporary.
  • Some medications, such as antibiotics or antiepileptic drugs, may reduce the effectiveness of Leena. Inform your healthcare provider about all medications and supplements you are taking.

Side Effects of Leena

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Weight changes
  • Mood changes
  • Spotting or breakthrough bleeding

Uncommon/Severe Side Effects

  • Blood clots (leg pain, swelling, shortness of breath)
  • Stroke (sudden vision changes, trouble speaking, or weakness on one side of the body)
  • Liver issues (yellowing of the skin or eyes, upper stomach pain)
  • High blood pressure

Risks and Warnings of Leena

  • Blood Clots: The risk of blood clots is higher in women who take combination oral contraceptives, particularly in those who smoke or are overweight. Women who smoke should avoid using Leena if they are over 35 years old.
  • Cardiovascular Risks: The risk of heart attack or stroke is higher in women over 35 who smoke. These women should consider alternative contraceptive methods.
  • Liver Damage: Combination oral contraceptives may cause liver damage or benign liver tumors. Regular liver function tests may be required for women with a history of liver issues.
  • Breast and Cervical Cancer: Prolonged use of hormonal contraceptives may slightly increase the risk of breast and cervical cancer. Regular screening is recommended.

Interactions with Leena

Common Drug Interactions

  • Antibiotics (e.g., rifampin): May reduce the effectiveness of Leena, increasing the risk of pregnancy.
  • Antiepileptic drugs (e.g., carbamazepine, phenytoin): May decrease the contraceptive efficacy of Leena.
  • St. John’s Wort: Can lower the effectiveness of Leena, increasing the risk of pregnancy.
  • HIV medications: Some antiretrovirals may interfere with the effectiveness of oral contraceptives.

Alternatives to Leena

  • Ortho-Novum: Another combination oral contraceptive with a different formulation of estrogen and progestin.
  • Loestrin: A lower-dose estrogen combination contraceptive pill.
  • Depo-Provera: A progestin-only injectable contraceptive given every 3 months.
  • Nexplanon: A progestin-only contraceptive implant that provides long-term protection.