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Lanthanum Carbonate
Lanthanum carbonate is a medication used primarily to manage hyperphosphatemia (high phosphate levels) in patients with chronic kidney disease (CKD) who are on dialysis. It helps to reduce phosphate absorption from the gastrointestinal tract, thereby lowering serum phosphate levels.
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Frequently Asked Questions
How long does it take for lanthanum carbonate to work?
Patients may start to see improvements in serum phosphate levels within a few days to weeks of starting treatment.
Can I take lanthanum carbonate with other medications?
Always consult your healthcare provider before combining lanthanum carbonate with other medications, especially those taken orally.
What should I do if I miss a dose of lanthanum carbonate?
If you miss a dose, take it as soon as you remember, but only if it is within the time frame of your next scheduled dose. Do not double up on doses.
Is it safe to use lanthanum carbonate during pregnancy?
Lanthanum carbonate should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can lanthanum carbonate cause weight gain?
Weight gain is not commonly associated with lanthanum carbonate. Any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Lanthanum Carbonate Work?
Lanthanum carbonate works by binding to dietary phosphate in the gastrointestinal tract, forming insoluble lanthanum phosphate. This process prevents the absorption of phosphate into the bloodstream, thereby lowering serum phosphate levels in patients with impaired kidney function.
Common Dosages
- Chewable tablets: Common dosages include 500 mg and 750 mg.
Typical Dosing
- The usual starting dose is 500 mg taken orally three times daily with meals. The dosage may be adjusted based on serum phosphate levels, up to a maximum recommended dose.
Typical Dosing
FDA Approved Indications
- Control of hyperphosphatemia in patients with chronic kidney disease on dialysis.
Who Shouldn't Take Lanthanum Carbonate?
- Known hypersensitivity to lanthanum carbonate or any components of the formulation
- Intestinal obstruction or severe gastrointestinal disorders
Advice From The Pharmacist
- Patients should be advised to chew the tablets thoroughly before swallowing and to take them with food to maximize effectiveness.
- Discuss the importance of regular monitoring of serum phosphate levels to assess treatment effectiveness.
- Inform patients about potential side effects, including gastrointestinal disturbances.
Side Effects of Lanthanum Carbonate
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Abdominal pain
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis)
- Gastrointestinal obstruction (rare)
Risks and Warnings of Lanthanum Carbonate
- Gastrointestinal Issues: Monitor for signs of gastrointestinal obstruction or severe discomfort.
- Regular Monitoring: Routine monitoring of phosphate and calcium levels is important to avoid complications.
Interactions with Lanthanum Carbonate
Common Drug Interactions
Other Medications: Lanthanum carbonate may reduce the absorption of other oral medications; patients should space dosing of other medications appropriately.
Alternatives to Lanthanum Carbonate
- Other Phosphate Binders: Such as calcium acetate or sevelamer for managing hyperphosphatemia.
- Dietary Management: Reducing dietary phosphate intake may also help control phosphate levels.
