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Lanoxin
Lanoxin (digoxin) is a cardiac glycoside used primarily to treat heart failure and certain types of arrhythmias, particularly atrial fibrillation and atrial flutter. It helps improve the efficiency and strength of heart contractions, leading to better blood circulation.
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Frequently Asked Questions
How long does it take for Lanoxin to start working?
may take longer to assess.
Can I take Lanoxin with other medications?
Always consult your healthcare provider before combining Lanoxin with other medications, especially those affecting heart function.
What should I do if I miss a dose of Lanoxin?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Is it safe to use Lanoxin during pregnancy?
Lanoxin should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Lanoxin cause weight gain?
Weight gain is not a common side effect of Lanoxin. Any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Lanoxin Work?
Digoxin increases the force of myocardial contraction by inhibiting the sodium-potassium ATPase pump. This inhibition leads to an increase in intracellular calcium concentrations, enhancing cardiac contractility. Additionally, it has effects on the autonomic nervous system, which can slow heart rate and improve rhythm.
Common Dosages
- Tablets: Common dosages include 0.125 mg and 0.25 mg.
- Oral solution: Contains 0.05 mg/mL of digoxin.
Typical Dosing
- The usual starting dose for adults may be 0.5 to 1 mg given in divided doses over the first 24 hours, followed by a maintenance dose of 0.125 to 0.25 mg daily, depending on renal function and patient response.
Typical Dosing
FDA Approved Indications
- Heart failure: To improve symptoms and reduce hospitalizations.
- Atrial fibrillation: To control ventricular rate.
Who Shouldn't Take Lanoxin?
- Known hypersensitivity to digoxin or any components of the formulation
- Ventricular fibrillation
- Certain types of heart block without a pacemaker
Advice From The Pharmacist
- Patients should be advised to take Lanoxin exactly as prescribed, and to avoid missing doses, as maintaining steady blood levels is crucial for effectiveness.
- Monitor for signs of toxicity, such as nausea, vomiting, confusion, or vision changes (e.g., yellow-green halos).
- Encourage patients to check their pulse before taking the medication; if it is below 60 beats per minute, they should contact their healthcare provider.
Side Effects of Lanoxin
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Dizziness
Uncommon/Severe Side Effects
- Symptoms of digoxin toxicity (e.g., severe nausea, visual disturbances, confusion)
- Heart block or bradycardia
Risks and Warnings of Lanoxin
- Toxicity: Regular monitoring of digoxin levels and renal function is essential to prevent toxicity.
- Electrolyte Imbalance: Conditions such as hypokalemia (low potassium) can increase the risk of digoxin toxicity; monitor electrolytes closely.
Interactions with Lanoxin
Common Drug Interactions
- Diuretics: Use with potassium-depleting diuretics can increase the risk of digoxin toxicity.
- Certain Antiarrythmics: Medications like verapamil or amiodarone may increase digoxin levels.
Alternatives to Lanoxin
- Other Heart Failure Medications: Such as ACE inhibitors or beta-blockers for managing heart failure.
- Antiarrythmics: Such as beta-blockers or calcium channel blockers for rate control in atrial fibrillation.
