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Kurvelo

Kurvelo is a combination oral contraceptive that contains ethinyl estradiol and levonorgestrel. It is primarily used for preventing pregnancy and may also be indicated for regulating menstrual cycles, reducing menstrual cramps, and managing acne in women who desire contraception. Kurvelo works by preventing ovulation, thickening cervical mucus, and altering the uterine lining to make it less suitable for implantation.

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Frequently Asked Questions

How effective is Kurvelo at preventing pregnancy?
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Kurvelo is over 99% effective when taken correctly. Missing pills or inconsistent use can reduce its effectiveness.

What should I do if I miss a dose?
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If you miss a pill, take it as soon as you remember and take the next pill at the usual time. If you miss two or more pills, follow the instructions in the package insert and use backup contraception for the next 7 days.

Can Kurvelo help regulate my menstrual cycle?
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Yes, Kurvelo can help regulate your period and reduce the severity of menstrual cramps.

Can Kurvelo be used to treat acne?
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Yes, Kurvelo may help manage acne in women who also desire oral contraception.

Is Kurvelo safe for long-term use?
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Kurvelo can be safe for long-term use under the supervision of a healthcare provider, with regular monitoring for any potential side effects.

Comprehensive Drug Guide

How Does Kurvelo Work?

  1. Prevents ovulation: The hormones inhibit the release of eggs from the ovaries.
  2. Thickens cervical mucus: This makes it more difficult for sperm to enter the uterus.
  3. Alters the uterine lining: The lining becomes less suitable for implantation, reducing the likelihood of pregnancy.

Common Dosages

  • 21 active pills: Containing 0.15 mg of levonorgestrel and 0.02 mg of ethinyl estradiol.
  • 7 inactive pills: Taken during the last week to allow for a withdrawal bleed.

Typical Dosing

  • Take 1 active pill daily for 21 days, followed by 1 inactive pill daily for 7 days. A withdrawal bleed usually occurs during this time.
  • Start the next pack immediately after finishing the inactive pills to maintain contraceptive protection.

Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy
  • Regulation of menstrual cycles
  • Reduction of menstrual cramps
  • Management of acne in women who desire oral contraception

Who Shouldn't Take Kurvelo?

  • A history of blood clots, deep vein thrombosis (DVT), or pulmonary embolism (PE)
  • Uncontrolled high blood pressure
  • Liver disease or liver tumors
  • Breast cancer or other hormone-sensitive cancers
  • Smoking and over the age of 35, due to increased cardiovascular risks

Advice From The Pharmacist

  • Take Kurvelo at the same time every day to ensure maximum effectiveness. If you miss a pill, follow the instructions in the package insert or contact your healthcare provider for guidance.
  • Use backup contraception (such as condoms) if you miss two or more pills or start a new pack late.
  • Kurvelo does not protect against sexually transmitted infections (STIs); use condoms to reduce the risk of STIs.
  • Some women may experience spotting or breakthrough bleeding during the first few months of use, which typically resolves as the body adjusts to the hormones.
  • Inform your healthcare provider about all medications and supplements you are taking, as some drugs may interact with Kurvelo.

Side Effects of Kurvelo

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Mood changes
  • Weight fluctuations
  • Spotting or breakthrough bleeding

Uncommon/Severe Side Effects

  • Blood clots (symptoms include leg swelling, chest pain, or shortness of breath)
  • Stroke (symptoms include sudden numbness or weakness, trouble speaking, or severe headache)
  • Liver problems (indicated by jaundice, dark urine, or abdominal pain)

Risks and Warnings of Kurvelo

  • Cardiovascular Risks: The risk of blood clots is higher in women taking combination oral contraceptives, particularly those who smoke or have a history of clotting disorders. Women over 35 who smoke should consider alternative contraceptive options.
  • Liver Issues: Liver function should be monitored in patients with a history of liver disease, as Kurvelo can exacerbate liver conditions.
  • Cervical Cancer: Long-term use of hormonal contraceptives may slightly increase the risk of cervical cancer; regular screenings are advised.

Interactions with Kurvelo

Common Drug Interactions

  • Antibiotics (e.g., rifampin): Certain antibiotics can reduce the effectiveness of Kurvelo, leading to an increased risk of unintended pregnancy.
  • Antiepileptic drugs (e.g., carbamazepine, phenytoin): These medications may decrease the efficacy of Kurvelo.
  • St. John’s Wort: This herbal supplement can also reduce the effectiveness of oral contraceptives.

Alternatives to Kurvelo

  • Loestrin: Another combination oral contraceptive with different hormone formulations.
  • Ortho Tri-Cyclen: A combination contraceptive that varies hormone levels throughout the cycle.
  • Depo-Provera: A progestin-only injectable contraceptive given every three months.
  • IUDs: Intrauterine devices like Mirena or ParaGard, which provide long-term contraception without daily pills.