You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
Invokamet XR
Invokamet XR is a combination medication that contains canagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin hydrochloride, a biguanide. It is used to improve glycemic control in adults with type 2 diabetes mellitus. This extended-release formulation allows for once-daily dosing, making it a convenient option for patients.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with Invokamet XR ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for Invokamet XR to start working?
Patients may begin to see improvements in blood glucose levels within a few days, but optimal control may take longer.
What should I do if I miss a dose of Invokamet XR?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Is it safe to use Invokamet XR during pregnancy?
Invokamet XR should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Invokamet XR cause weight gain?
Weight gain is not common with Invokamet XR; in fact, it may help with weight management. Any significant changes in weight should be discussed with a healthcare provider.
Comprehensive Drug Guide
How Does Invokamet XR Work?
- Canagliflozin works by inhibiting the SGLT2 protein in the kidneys, reducing glucose reabsorption and promoting urinary excretion of glucose, which lowers blood sugar levels.
- Metformin decreases hepatic glucose production and improves insulin sensitivity, helping to lower blood sugar levels.
Common Dosages
- Extended-release tablets: Common dosages include 50 mg/1000 mg, 150 mg/1000 mg, and 150 mg/500 mg of canagliflozin/metformin.
Typical Dosing
- The typical starting dose is 150 mg of canagliflozin and 1000 mg of metformin taken once daily, which may be adjusted based on glycemic response and tolerability.
- Maximum doses may vary; the healthcare provider will determine the appropriate dosing regimen for each patient.
Typical Dosing
FDA Approved Indications
- Improvement of glycemic control in adults with type 2 diabetes mellitus, used in conjunction with diet and exercise.
Who Shouldn't Take Invokamet XR?
- Known hypersensitivity to canagliflozin, metformin, or any components of the formulation
- Severe renal impairment (eGFR < 30 mL/min)
- Active or history of metabolic acidosis, including diabetic ketoacidosis
Advice From The Pharmacist
- Patients should be advised to take Invokamet XR with food to reduce the risk of gastrointestinal side effects.
- Encourage regular monitoring of blood glucose levels to evaluate treatment effectiveness.
- Advise patients to stay hydrated and report any signs of dehydration, such as dizziness or reduced urination.
Side Effects of Invokamet XR
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort
- Urinary tract infections
Uncommon/Severe Side Effects
- Lactic acidosis (a rare but serious condition associated with metformin)
- Severe allergic reactions (anaphylaxis)
- Kidney problems, including acute kidney injury
Risks and Warnings of Invokamet XR
- Lactic Acidosis: Monitor for symptoms such as weakness, fatigue, and unusual muscle pain, especially in patients with renal impairment or other risk factors.
- Renal Function: Assess renal function prior to initiation and periodically during treatment, as SGLT2 inhibitors can impact kidney health.
- Risk of Amputations: There have been reports of increased risk of lower limb amputations in patients taking canagliflozin; patients should be educated about foot care.
Interactions with Invokamet XR
Common Drug Interactions
- Other Antidiabetic Medications: Careful monitoring is required when using Invokamet XR with other diabetes medications to avoid hypoglycemia.
- Diuretics: May increase the risk of dehydration and renal impairment when combined with SGLT2 inhibitors.
Alternatives to Invokamet XR
- Metformin alone: For patients who do not require SGLT2 inhibition.
- Other SGLT2 Inhibitors: Such as empagliflozin or dapagliflozin for managing blood sugar levels.
- GLP-1 Receptor Agonists: Such as liraglutide for additional options in diabetes management.
