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Igalmi

Igalmi, also known under the brand name Dupixent, is a type of medication known as immunosuppressant. It's used to lower the immune response in your body to treat conditions like moderate to severe atopic dermatitis (eczema), chronic rhinosinusitis, and asthma. Common side effects might include redness or swelling at the injection site, cold sores, and eye inflammation. Your doctor will usually make sure the benefits outweigh these issues.

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Frequently Asked Questions

Can I take Igalmi if I have a helminth infection?
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No, you should deal with the infection first, as Igalmi can make it worse.

Can Igalmi make me gain weight?
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No, Igalmi should not make you gain weight. If you're noticing unexplained weight gain, be sure to talk to your doctor.

What should I do if I miss an Igalmi dose?
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If you forget to take a dose, just take it as soon as you remember. If it's close to your next dose, skip the missed dose.

Comprehensive Drug Guide

How Does Igalmi Work?

Igalmi is a monoclonal antibody that blocks interleukin4 and interleukin13, chemical messengers responsible for itchiness, inflammation, and other unwanted immune responses.

What is Igalmi Used For?

FDA indications: Igalmi is used to treat moderate to severe atopic dermatitis (eczema) that's not well controlled with topical therapies, and in adults with severe asthma. It can also be used for chronic rhinosinusitis with nasal polyps.

Offlabel uses: Given its immunosuppressive properties, your physician may prescribe it in the management of other immunerelated disorders.

Common Dosages

Dupixent injections: 300mg

Typical Dosing

FDA Approved Indications

  • Atopic dermatitis and asthma: 300mg every other week.
  • Chronic rhinosinusitis with nasal polyps: 300mg every other week or 600mg every other week depending on severity.

Off-Label Uses

  • The doses for offlabel use will be determined based on the condition and the effect the doctor wants to achieve.

Who Shouldn't Take Igalmi?

  • Have a known hypersensitivity to Igalmi or any of its components.
  • Have a helminth (parasitic worm) infection.
  • Are pregnant, planning to become pregnant, or are breastfeeding (it's not known whether Igalmi can harm the baby).

Advice From The Pharmacist

  • Taking care of your injection site can minimize the likelihood of any unpleasant side effects.
  • Store your medication in your fridge, never freeze it, and ensure your drug is compatible with temp changes.
  • Don?t suddenly stop taking Igalmi without consulting your doctor, tapering may be necessary.
  • Always use the medicine the same day you take it out of the fridge. Make sure to let it reach room temperature before using it.
  • Make sure not to shake the medication. It should be colorless to slightly yellow and may contain tiny white or clear particles.
  • If you get cold sores or eye inflammation, consult with your healthcare provider.

Side Effects of Igalmi

Common Side Effects

  • You might have slight swelling, redness, or a little pain where the medication was injected.
  • Cold sores and fever blisters might pop out on your lips or in your mouth.
  • You may experience eye inflammation if this happens, contact your doctor.

Uncommon/Severe Side Effects

  • Uncommon side effects:
  • Impaired wound healing.
  • Rare side effects:
  • Some people may have a reaction that is likely an allergic reaction, such as having a rash, itching, or swelling.
  • Severe side effects:
  • Signs of a serious allergic reaction like a rash, itching or swelling of the face/tongue/throat, severe dizziness, or trouble breathing need immediate medical attention.

Risks and Warnings of Igalmi

  • If you have a hypersensitivity to Igalmi or any of its ingredients, don't take this medication.
  • Those with a helminth infection need to be treated for the infection before starting on Igalmi.
  • Because there's not enough information on the risks to a pregnancy or breastfeeding infant, be sure to discuss with your healthcare provider if you're pregnant, planning to become pregnant, or breastfeeding.

Interactions with Igalmi

Common Drug Interactions

  • There aren't any specific known drug interactions, but make sure to let your doctor know about all the medications you're taking.

Alternatives to Igalmi

  • Dupixent
  • Eucrisa
  • Elidel
  • Otezla
  • Stelara
  • Humira