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Hydrocortisone Ace-Pramoxine

Hydrocortisone Ace-Pramoxine is a topical medication used to provide relief from itching, inflammation, and discomfort associated with various skin conditions, including hemorrhoids and other anal or rectal irritations. It combines hydrocortisone, a corticosteroid that reduces inflammation, with pramoxine, a local anesthetic that numbs the affected area.



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Frequently Asked Questions

Other Topical Treatments: Such as witch hazel or other hydrocortisone formulations. Oral Medications: Pain relievers such as acetaminophen or ibuprofen for symptom management.
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Many patients may start to notice relief within a few hours of application, although complete effects can take longer.

Many patients may start to notice relief within a few hours of application, although complete effects can take longer.
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Consult your healthcare provider for guidance, as the use during pregnancy should be evaluated based on individual circumstances.

What should I do if I experience severe irritation after using the cream?
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Discontinue use immediately and contact your healthcare provider for further evaluation.

Are there any specific storage instructions for Hydrocortisone Ace-Pramoxine?
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Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

Is Hydrocortisone Ace-Pramoxine safe for long-term use?
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Long-term use should be monitored by a healthcare provider to assess efficacy and minimize the risk of side effects.

Comprehensive Drug Guide

How Does Hydrocortisone Ace-Pramoxine Work?

Hydrocortisone works by inhibiting the inflammatory response and reducing redness, swelling, and itching. Pramoxine provides localized numbness by blocking nerve signals in the area where it is applied, which helps alleviate pain and discomfort.



Common Dosages

  • Topical cream or ointment: Common concentrations include 1% hydrocortisone and 1% pramoxine.

Typical Dosing

The typical dosing for Hydrocortisone Ace-Pramoxine is:

  • For Anorectal Conditions: Apply a thin layer to the affected area up to four times daily as needed for symptom relief.


Typical Dosing

FDA Approved Indications

  • Relief of itching and discomfort associated with hemorrhoids and other anorectal conditions.


Who Shouldn't Take Hydrocortisone Ace-Pramoxine?

  • Hypersensitivity: Known hypersensitivity to hydrocortisone, pramoxine, or any components of the formulation.
  • Infections: Should not be used on infected areas unless appropriately treated.


Advice From The Pharmacist

  • How to Use: Apply the cream or ointment gently to the affected area. Avoid vigorous rubbing to minimize irritation.
  • Monitor Symptoms: If symptoms persist or worsen after treatment, consult a healthcare provider.
  • Storage: Store at room temperature, away from moisture and direct sunlight.


Side Effects of Hydrocortisone Ace-Pramoxine

Common Side Effects

  • Local irritation or burning at the application site
  • Dryness or peeling of the skin
  • Itching


Uncommon/Severe Side Effects

  • Severe allergic reactions: Such as rash, itching, or difficulty breathing.


Risks and Warnings of Hydrocortisone Ace-Pramoxine

  • Avoid in Certain Conditions: Use with caution in patients with a history of recurrent infections or skin conditions.
  • Not for Generalized Itching: If the cause of itching is unknown, seek medical advice before using.


Interactions with Hydrocortisone Ace-Pramoxine

Common Drug Interactions

Drug Interactions: No significant drug interactions are noted; however, inform your healthcare provider about all medications and topical products you are using.

Alternatives to Hydrocortisone Ace-Pramoxine

  • Other Topical Treatments: Such as witch hazel or other hydrocortisone formulations.
  • Oral Medications: Pain relievers such as acetaminophen or ibuprofen for symptom management.